Results 211 to 220 of about 2,268,216 (242)

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Successful perfluorocarbon-assisted retrieval of a subretinal dexamethasone implant during retinal detachment repair. [PDF]

J Surg Case Rep
Keshavamurthy R, Cheng AMS, Chalam KV.
europepmc   +1 more source

Systematic Position Mapping of Split CRISPR‐Cas12a Activators Enables Highly Sensitive miRNA Detection and Cancer Cell Stratification

Advanced Science, EarlyView.
ABSTRACT Amplification‐free Cas12a diagnostics with split crRNA enable rapid and programmable target recognition, yet insufficient understanding of DNA activator architecture prevents predictable control over trans‐cleavage activity and sensitivity. Here we systematically map over 200 split DNA activator configurations by introducing nicks at every ...
Xiaoyan Tang, Zhe Li, Yuning Lu, Miao Ma, Zijian Mo, Jiajun Ke, Xinyu Luan, Tiangang Luan, Junqiu Zhai   +8 more
wiley   +1 more source

Data-Driven Critical Evaluation of the General Solubility Equation. [PDF]

J Chem Inf Model
Bertsch-Aguilar E, Quirós N, Schosinsky F, Pinheiro S, Medina-Franco JL, Zamora WJ.   +5 more
europepmc   +1 more source

Short-read genome skimming enables molecular barcoding of old myxomycete collections. [PDF]

IMA Fungus
Leontyev DV, Schnittler M, Shchepin ON.
europepmc   +1 more source

5-Formylcytosine functions as a chemical regulator of nucleosome positioning. [PDF]

Nat Commun
Furuhata T, Lin Y, Hino G, Okamoto A.
europepmc   +1 more source

ddOTs: A multiplexed quantitative ddPCR approach for resolving overlapping hepatitis B virus transcripts to decipher cccDNA-driven transcription. [PDF]

PLoS Pathog
Sarica N, Lopez O, Diogo Dias J, Boschetti V, Meki I, Jay B, Petitjean G, Durantel D, Neuveut C.   +8 more
europepmc   +1 more source

CRUSH-Cleavage Rules Using SMIRKS Heuristics: an enhanced molecular fragmentation algorithm. [PDF]

J Cheminform
López-López E, Medina-Franco JL, Miljković F.   +2 more
europepmc   +1 more source

Fragments

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Enhancement of RecET-mediated in vivo linear DNA assembly by a xonA mutation. [PDF]

PLoS One
Sawitzke JA, Costantino N, Caballero AC, Hutchinson E, Barenghi A, Thomason LC, Court DL.   +6 more
europepmc   +1 more source