Results 61 to 70 of about 259,384 (291)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Extending of TAM Model in E-Filing Adoption

Riset Akuntansi dan Keuangan Indonesia
Digitalization and modernization supported by the development of the internet provide important value for the tax sector and taxpayers. This not only affects awareness and compliance but also its relevance to state revenue.
Edy Purwo Saputro, Candra Kusuma Wardana, Dewi Probowati Setyaningrum, Ahmad Febriyanto   +3 more
doaj   +1 more source

ANALISIS MODEL PENERIMAAN PENGGUNA SISTEM PELAPORAN PAJAK ONLINE

Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2016
Direktorat Jenderal Pajak saat ini telah menerapkan e-SPT dan e-Filing sebagai sarana digitalisasi dan otomasi pelaporan pajak. Untuk meningkatkan transformasi bisnis proses dalam sistem pelayanan perpajakan dari sistem manual ke digital, diperlukan ...
Muhammad Malik Hakim
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Peran E-Filing Dalam Pelaporan Wajib Pajak Tahunan

Jurnal Perpajakan dan Keuangan Publik
Direktorat Jenderal Pajak memberikan kemudahan bagi Wajib Pajak untuk melaporkan kewajiban perpajakannya sehingga tidak perlu datang secara langsung ke Kantor Pelayanan Pajak.
Nesy Aida Rahman, Imahda Khoiri Furqon
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Tax E-Filing System Acceptance Level on the Taxation Compliance: An Application of the UTAUT Approach

Journal the Winners, 2019
This research aimed to analyze the acceptance level of the tax e-filing system on the tax compliance of the individual taxpayer. UTAUT had underpinned this research that consisted of the aspects of Performance Expectancy (PE), Effort Expectancy (EE ...
Natasya Natasya, Elia Madatu Tandililing, Michael Angelus, Kevin Kevin   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

PENGARUH PERSEPSI KEGUNAAN DAN PERSEPSI KEMUDAHAN PENGGUNAAN TERHADAP HUBUNGAN ANTARA PERSEPSI PENERAPAN SISTEM E-FILING DENGAN TINGKAT KEPATUHAN WAJIB PAJAK BADAN YANG DIMEDIASI OLEH PERILAKU WAJIB PAJAK (Studi Kasus Pada Kantor Pelayanan Pajak Pratama Jakarta Pulo Gadung)

Profita, 2017
The purpose of this study is to find empirical evidence on: 1) The effect of perception of the application of e-filing system to taxpayer compliance; 2) Effect of perception of e-filing system implementation on Taxpayer's behavior; 3) The influence of ...
Veronica Nensi Panca Herina
doaj  

TAXPAYERS’ PERCEPTIONS TOWARDS E-FILING SYSTEM APPLICATION: A DECOMPOSED THEORY OF PLANNED BEHAVIOR (DTPB) APPROACH

Profit: Jurnal Administrasi Bisnis, 2019
 This research aimed to examine the perceptions of taxpayers in applying the Annual Tax Return e-Filing system with the approach of Decomposed Theory of Planned Behavior (DTPB) model by Taylor and Todd (1995). This research is the development of the ...
Latifah Hanum
doaj   +1 more source