Results 31 to 40 of about 1,744,821 (286)

The formation mechanism of geological disasters on loess fill slopes revealed by the deformation characteristics of remolded loess under different stress paths

Frontiers in Earth Science
In recent years, geological disasters on loess fill slopes have occurred from time to time, which has attracted widespread attention. In order to deeply understand its deformation and failure laws and promote the disaster prevention and mitigation work ...
Shuran Meng, Shuran Meng, Dunyu Lv, Dunyu Lv, Ru Liu, Mancang Yu, Mancang Yu, Jianyu Zhang, Jianyu Zhang   +8 more
doaj   +1 more source

Delayed instabilities of water-retaining earth structures

Frontiers in Built Environment, 2022
Aging earth fill dams that were constructed in the mid-1950’s are beginning to show signs of instability associated with time-dependent degradation of shear strength.
Irene Olivia Ubay-Anongphouth, Marolo Alfaro   +1 more
doaj   +1 more source

Hydrological and failure process of loess-bedrock fill slopes under continuous heavy rainfall

Journal of Rock Mechanics and Geotechnical Engineering
During extensive gully land consolidation projects on China's Loess Plateau, many loess-bedrock fill slopes were formed, which frequently experience shallow landslides induced by rainfall.
Zhiyu Guo, Qiangbing Huang, Daijin Yu, Yue Liu, Mingxiang Xu, Qingyu Xie   +5 more
doaj   +1 more source

Application research of a prestressed anchor cable‐pile‐slab wall supporting structure for multistage high fill slopes

Engineering Reports, 2020
When carrying out engineering constructions in a mountainous area with complex geological conditions, high fill slopes commonly need to be strengthened. At present, several of the main supporting structures have unique defects and shortcomings when used ...
Yan‐peng Zhu, Zhen‐hong Wei, Qiao‐hong Zhu   +2 more
doaj   +1 more source

Factors Affecting Earthwork Volume in Forest Road Construction on Steep Terrain

Land, 2023
Forest roads, as a prerequisite for high-quality forest management, should be optimally distributed in order to avoid negative environmental impacts and to best fulfill their task.
Ivica Papa, Rodolfo Picchio, Mihael Lovrinčević, David Janeš, Tibor Pentek, Dino Validžić, Rachele Venanzi, Andreja Đuka   +7 more
doaj   +1 more source

Analysis of disaster risk to oil and gas pipelines and the effect of CFG reinforcement on high-fill slopes in Yunnan

Zhongguo dizhi zaihai yu fangzhi xuebao
The study aims to investigate the stability of high fill slopes and their impact on oil and gas pipelines at the foot of the slopes in a key construction project located in Anning City, Yunnan Province.
Zhangzhen LIU, Fayou A, Jing ZHANG, Dashen YANG, Xiaobo LIU   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Stability Analysis and Application of Two-Stage Support on The High Fill Slope

Journal of Physics: Conference Series, 2019
This paper relies on the two-stage slope project, which is in Sanmenxia. The first grade slope is reinforced by soil nailing, multi-row piles and buttress retaining wall support scheme are adopted for the second stage subsequent fill slope, finite ...
Guo Yuan-cheng, Du Hao, Liu Yun-hua, Qiu Qing, Jin Junwei   +4 more
semanticscholar   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source