Results 71 to 80 of about 208,745 (304)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Studies on SI engine simulation and air/fuel ratio control systems design [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.More stringent Euro 6 and LEV III emission standards will immediately begin execution on 2014 and 2015 respectively.
Bai, Yang, Yang Bai
core
, 2017 High aspect ratio three-dimensional micro- and nanopatterns have important applications in diverse fields. However, fabricating these structures by a nanoimprinting method invites problems like collapse, dislocation, and defects. Finite-element analysis (
Minqi Yin, Hongwen Sun, Haibin Wang
core +1 more source
EnergiesTo support the integration of high shares of renewable energy and enhance the operational flexibility of thermal power systems, thermosyphon have been considered as promising high-efficiency heat transfer components for thermal energy storage ...
Yi Ding, Jianlong Ma
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
, 2019 The E/e’ ratio has an established role in the assessment of left ventricular filling pressure (LVFP) in stable patients, but its accuracy in acute myocardial ischemia is less well established.
Prasad, Sandhir B. +10 more
core +1 more source
Compressive strength of filling material.
, 2023 This paper aims to analyze the roof stability when the reclaimed working face passes through abandoned roadway. The mechanical model of main roof in abandoned roadway was established for the purpose of theoretical analyses. To ensure the stability of the
Lei Xu (78676) +5 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Expansion rate of filling material.
, 2023 This paper aims to analyze the roof stability when the reclaimed working face passes through abandoned roadway. The mechanical model of main roof in abandoned roadway was established for the purpose of theoretical analyses. To ensure the stability of the
Lei Xu (78676) +5 more
core +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source