Results 51 to 60 of about 191,101 (309)

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

Advanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang, Qiyue Zhang, Yueyang Qiu, Haocheng Suo, Zengqian Liu, Bing Bai, Qiang Wang, Qing Zhou   +7 more
wiley   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Bisphosphonate: Brief Review of Its Development for Usage in Dentistry [PDF]

, 2013
Bisphosphonate (BP) is a class of drug that prevent the loss of bone mass. It inhibits the resorption of bone by encouraging osteoclast to undergo apoptosis.
Utari, Tita Ratya; Faculty of Medical and Health Sciences, Muhammadiyah Yogyakarta University, Yogyakarta 55813
core   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Double Helix Structure for Stable Flexural Actuation in Soft Robotics

Advanced Intelligent Systems, EarlyView.
This work introduces a double‐helical architecture for soft robotic actuators that enhances twisting resistance, increases output force, and minimizes undesired deformation. Actuators driven by shape‐memory alloy wires exhibit a roughly fivefold higher torsional/flexural stiffness ratio and 50% greater force output.
Louis Plottel, Richard Desatnik, Dinesh K. Patel, Philip LeDuc, Carmel Majidi   +4 more
wiley   +1 more source

EFFECTIVITY OF TWO BLEACHING AGENT OF 10% CARBAMIDE PEROXIDE WITH AND WITHOUT POTASSIUM NITRATE-FLUORIDE (CLINICAL STUDY) [PDF]

, 2015
Tooth bleaching has become a popular treatment for esthetic improvement in dentistry. There are several 10% carbamide peroxide bleaching agents that are available in Indonesia which contained potassium nitrate-fluoride or without potassium nitrate ...
Usman, Munyati; Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Hoesin, Safrida; Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Lusiyanti, Ayus; Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430   +2 more
core   +1 more source

Concentration of nitric oxide in patients’ saliva from various metal restorative activities in the oral cavity [PDF]

Acta Medica Academica, 2011
Objective. Th e aim of this paper is to determine the concentration ofnitric oxide (NO) in the saliva of subjects resulting from the presence of various metal restorative activities in the oral cavity. Patients and methods. Th e research was conducted on
Enes Pašić, Amira Dedić, Jasminko Huskić, Sanja Hadžić   +3 more
doaj   +1 more source

PERAWATAN KONSERVASI GIGI PADA PASIEN GOLONGAN USIA LANJUT [PDF]

, 2015
The need for conservative dentistry treatment for the elderly is different to the need of the other age group. Usually the main problem is root surface caries which in the future will increase in accordance with the demographic changes so that the aging ...
Sundoro, Edi Hartini; Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430
core   +1 more source