Results 31 to 40 of about 887,707 (303)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Covering the Israeli–Palestinian Conflict: A Critical Discourse Analysis of Al Jazeera English and BBC’s Online Reporting on the 2023 Gaza War

Journalism and Media
The Hamas surprise attack on southern Israel on 7 October 2023, and the Israeli military response unleashed a catastrophic episode of the Israeli–Palestinian conflict and exacerbated broader tensions in the region. This study compares Al Jazeera English (
Kareem El Damanhoury, Faisal Saleh, Madeleine Lebovic   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Introduction. Waste in Films – Waste after Films: Before the War

Images, 2023
When we invited interested authors to contribute to the special issue titled “Waste in Films – Waste after Films,” we expected papers about waste shown in fictional films and in the real world, and in every potential “transitional” discursive form.
Pietari Kääpä, Marek Kaźmierczak
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Scenes of Translation: The Politics of Representation in Contemporary Dramaturgy

Tiyatro Eleştirmenliği ve Dramaturji Bölümü Dergisi
In the last decades, performers on European and US-American stages have tended to speak explicitly on behalf of others instead of portraying them. Those privileged enough to take the stage often do so in order to turn it into a political arena for making
Adam Czirak
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Forgetting History: Mediated Reflections on Occupy Wall Street

Media and Communication, 2017
This study examines how Occupy Wall Street (OWS) protestors’ practices and stated understanding of media act on social perceptions of networked media.
Michael S. Daubs, Jeffrey Wimmer
doaj   +1 more source

Emergent self-mediating classes in the digital semiosphere: Covid-19 conspiracies and the climate justice movement

Nordic Journal of Media Studies, 2021
In this article, we advocate for media studies to adopt a systematic evolutionary-complexity model, in order to link the study of human culture and knowledge practices to the biosphere and geosphere, arguing that such global phenomena require a new kind ...
Hartley John, Ibrus Indrek, Ojamaa Maarja   +2 more
doaj   +1 more source

Sociolinguistics II: Deviance, Dystopia, And Democracy (LING82) Syllabus [PDF]

, 2018
This course builds upon foundational concepts in sociolinguistic theory to examine discourses of news and entertainment media, across science fiction and politics.
Thomas, Jamie A.
core   +2 more sources