Results 31 to 40 of about 1,024,385 (307)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Existence of Woman Filmmakers in Film Ecosystem of Bandung

open access: yesMudra: Jurnal Seni Budaya
The art of filmmaking is a creative process that involves collaboration from various parties and aspects. This also inspired women filmmakers to create their own works.
Rufus Goang Swaradesy   +1 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The past is always changing: An interview with Tom Gunning

open access: yesNECSUS, 2022
Tom Gunning is one of the most influential and widely cited film historians in the world with over 150 essays and publications on early cinema, the avant-garde, and film genres.
Malte Hagener, Annie van den Oever
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Surreal Dreams of a “Creative City” (or: How Camerimage Festival Tried to Convince Łódź to Stop Worrying and Love Modern Architecture)

open access: yesImages, 2015
Surreal Dreams of a “Creative City” (or: How Camerimage Festival Tried to Convince Łódź to Stop Worrying and Love Modern Architecture) The study focuses on the architectural projects proposed by the creators of Camerimage festival for Łódź – which is ...
Konrad Klejsa
doaj   +1 more source

Книжевноста, традицијата и популарната култура (преку првиот македонски игран филм Фросина) [PDF]

open access: yesInternational Journal of Slavic Studies, 2019
The phenomenon of transporting novels into a film medium to examples of writers - scriptwriters is an opportunity for analyzing the relation literature – film and the relation tradition - popular culture.
Bijlana Rajčinova-Nikolova
doaj   +1 more source

Sustainable Development for Film-Induced Tourism: From the Perspective of Value Perception

open access: yesFrontiers in Psychology, 2022
The tourism economy has become a new driving force for economic growth, and film-induced tourism in particular has been widely proven to promote economic and cultural development.
Kui Yi   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy