Results 41 to 50 of about 1,028,847 (307)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Analysing of players’ perceptions on game aesthetics
Game aesthetics is a crucial multidimensional concept in understanding player experience within the gaming industry. However, limited empirical research has examined how players perceive game aesthetics and to what extent these perceptions vary among ...
Li-Chuan Evelyn Mai +3 more
doaj +1 more source
Race, Sex, and Redemption in Monster\u27s Ball [PDF]
In this paper, we explore the way that interracial relationships between blacks and whites come to be represented as problematic for mainstream audiences.
Fisher, Celeste, Wiebe, Carole
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Film festivals have been understood as part of a global network where each event acts as a node. Their position depends on their relevance and hierarchies within the circuit.
Sebastián González Itier
doaj +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Surreal Dreams of a “Creative City” (or: How Camerimage Festival Tried to Convince Łódź to Stop Worrying and Love Modern Architecture) The study focuses on the architectural projects proposed by the creators of Camerimage festival for Łódź – which is ...
Konrad Klejsa
doaj +1 more source
Handmade films and artist-run labs. The chemical sites of film’s counterculture [PDF]
This article addresses handmade films and especially artist-run labs as sites of hands-on film culture that reactivate moments and materials from media history.
Catanese, Rossella, Parikka, Jussi
core
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Josef Fares’ Zozo as accented cinema [PDF]
In 2005, the Lebanese-Swedish filmmaker Josef Fares, who had attained recognition in Sweden through the immigrant comedies Jalla! Jalla! (2000) and Kopps (2003), presented his third feature film and first drama, Zozo, inspired by Fares’s own migration to
Alexander, Elizabeth Lindsay
core +1 more source

