Results 21 to 30 of about 4,889,906 (282)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Teaching History using Feature Films: The Ghanaian Experience

open access: yesJournal of Education, Management and Development Studies, 2022
This study examines the experiences of lecturers in using feature films to teach history in the University of Cape Coast. The study specifically sought to find out the availability of historical feature films for teaching history, the criteria regarding
Dugba Ransford Tei   +1 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Exploration of MAB phase formation in the Fe-Y-Al-B system using thin film materials libraries

open access: yesMaterials & Design
Inspired by the recent theoretical and experimental advancements in MAB phase materials design we investigate the Fe-Y-Al-B system in search for the theoretically predicted (Fe2/3Y1/3)2AlB2 in-plane ordered MAB phase.
Aurelija Mockute   +7 more
doaj   +1 more source

Thick Film Ni0.5Mn0.5−xSnx Heusler Alloys by Multi-layer Electrochemical Deposition

open access: yesScientific Reports, 2018
The design of multifunctional alloys with multiple chemical components requires controllable synthesis approaches. Physical vapor deposition techniques, which result in thin films (
Yijia Zhang, Patrick J. Shamberger
doaj   +1 more source

Combinatorial Techniques to Efficiently Investigate and Optimize Organic Thin Film Processing and Properties

open access: yesMolecules, 2013
In this article we present several developed and improved combinatorial techniques to optimize processing conditions and material properties of organic thin films. The combinatorial approach allows investigations of multi-variable dependencies and is the
Hans-Werner Schmidt   +4 more
doaj   +1 more source

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

open access: yesAdvanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed   +6 more
wiley   +1 more source

FILM LIBRARY

open access: yesInternational Journal of Clinical Practice, 1963
  +7 more sources

Towards a film literacy canon: identification and multicultural analysis of the contents used in film education with pre-university students in Spain

open access: yesCommunication & Society (Formerly Comunicación y Sociedad), 2019
In the absence of a state film education plan in Spain, there are numerous initiatives operating in the field of both formal and non-formal education, the aim of which is pedagogy through cinema and about cinema.
Tamara Moya-Jorge
doaj   +1 more source

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