Results 31 to 40 of about 1,006,284 (308)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
I think I am turning academic, I really think so... [PDF]
, 2007 In this 15 minute reflective film I consider how I might develop the documentary film form into a method of “writing” with video to articulate a more complex understanding of the world.
Hearing, Trevor
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Participatory Film Production as Media Practice
International Journal of Communication, 2013 This article uses a practice theory perspective to study new media creation through the case of participatory film production. Although a growing body of practice-related literature addresses user-generated content or online creative communities, the ...
Antoni Roig Telo
doaj +2 more sources
Eisler’s Notes on Hollywood and the Film Music Project, 1935-42
Current Musicology, 2008 In 1947, Hanns Eisler in collaboration with Theodor Adorno published a small but important book entitled Composing for the Films. The book represents a significant contribution to film studies, cultural criticism, and discipline of twentieth-century ...
Sally M. A. Bick
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Film Adaption and Transnational Cultures or Production: The Case of Guillermo Arriaga [PDF]
, 2016 The circulation of Latin American cinema in a transnational context has widened the options that actors and directors from the region have regarding their involvement in the different aspects of film production.
Chavez, Daniel
core +2 more sources
Resisting relocation and reconceptualising authenticity: the experiential and emotional values of the Southbank Undercroft London UK [PDF]
, 2017 The tagline, ‘You Can’t Move History: You Can Secure the Future’, encapsulated the battle at the heart of the campaign to retain the Southbank Undercroft skate spot in the light of planned redevelopment of the Southbank Centre, London.
Madgin, Rebecca +3 more
core +1 more source