Results 41 to 50 of about 1,852,725 (304)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Images, 2021 This study investigates how the directors of two selected case study films criticise the real-life remnants of patriarchy in the family sphere, in nominally gender-equal Yugoslavia.
Vesi Vuković
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Growth and Characterization of Lead Sulphide Thin Film for Solar Cell Fabrication [PDF]
, 2011 Lead Sulphide thin film was deposited on glass substrate prepared from lead acetate and thiourea solution using solut ion growth technique. XRD studies show that, films prepared are in nanocry s tal l ine range. Also the diffraction peaks are found to be
Uhuegbu, C. C.
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Screening Indigenous Australia: Space, Place and Media in Frances Calvert’s Talking Broken
Ilha do Desterro, 2016 Drawing on the fields of postcolonial studies and media theory, this article analyzes Frances Calvert’s 1990 documentary, Talking Broken, which, inter alia, looks at the role of space, place and media amongst Australia’s ‘other’ Indigenous minority ...
Peter Kilroy
doaj +1 more source
Liberating Bicycles in Niki Caro’s Whale Rider and in Haifaa Al Mansour’s Wadjda
Imaginations: Journal of Cross-Cultural Media Studies, 2020 Susan B. Anthony declared in 1896 that the bicycle “has done more to emancipate women than anything else in the world.” The comparative study of Whale Rider (2002) and Wadjda (2012) demonstrates that this liberating effect of the basic tool of ...
Doris Hambuch
doaj +1 more source
Paper Flowers: Jane Campion, Plant Life, and The Power of the Dog (2021)
Philosophies, 2022 Taking as its point of departure the place of the vegetal realm within Jane Campion’s filmmaking, this article attends to both living and artificial plants, homing in on the exquisitely crafted paper flowers of The Power of the Dog to explore their ...
Sarah Cooper
doaj +1 more source
, 2017 Since the progress in the fabrication techniques of thin-films of exotic materials such as strongly correlated heavy-fermion compounds, microscopic studies of the magnetic and electronic properties inside the films have been needed. Herein, we report the
Ikeda, Hiroaki +8 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source