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This paper focuses on two discrete bodies of work, Hani Susumu’s films of the late 1950s and Tsuchimoto Noriaki’s Minamata documentaries of the early 1970s, to trace the emergence of the cinéma vérité mode of participant ...
Justin Jesty
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HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Thickness dependent Curie temperatures of ferromagnetic Heisenberg films
We develop a procedure for calculating the magnetic properties of a ferromagnetic Heisenberg film with single-ion anisotropy which is valid for arbitrary spin and film thickness. Applied to sc(100) and fcc(100) films with spin S=7/2 the theory yields the
Callen +12 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Six exemplary works of film theory, published in 2018–19, receive consideration in this chapter: Johannes Riis and Aaron Taylor’s anthology Screening Characters: Theories of Character in Film, Television, and Interactive Media; Murray Pomerance’s Virtuoso: Film Performance and the Actor’s Magic; Jonathan Kirshner and Jon Lewis’s edited collection When ...
openaire +4 more sources
Happiness Studies and Wellbeing: A Lacanian Critique of Contemporary Conceptualisations of the Cure
Criticising the discourse of happiness and wellbeing from a psychoanalytic perspective, this article is in five parts. The first offers a brief philosophical genealogy of happiness, charting its diverse meanings from ancient Greece, through Medieval ...
Colin Wright
doaj
La technographie de Charles Dekeukeleire. Le rôle du cinéma dans la civilisation machinique
This article aims at introducing, defining and questioning the notion of “technography” developed through Charles Dekeukeleire’s writings. It refers to the Belgian filmmaker’s industrial works, produced from the 1930s and 1940s onwards.
Mathilde Lejeune
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Yuri Tynianov: Permanent Evolution. Selected Essays on Literature, Theory and Film
Book review
Isabel Jacobs
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A new two-dimensional (2D) germanium dioxide film has been prepared. The film consists of interconnected germania tetrahedral units forming a bilayer structure, weakly coupled to the supporting Pt(111) metal-substrate.
Freund, H. +8 more
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