Results 41 to 50 of about 1,235,428 (301)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Novel High Holding Voltage SCR with Embedded Carrier Recombination Structure for Latch-up Immune and Robust ESD Protection

Nanoscale Research Letters, 2019
A novel CMOS-process-compatible high-holding voltage silicon-controlled rectifier (HHV-SCR) for electrostatic discharge (ESD) protection is proposed and demonstrated by simulation and transmission line pulse (TLP) testing.
Zhuo Wang, Zhao Qi, Longfei Liang, Ming Qiao, Zhaoji Li, Bo Zhang   +5 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Ga-doped ZnO films by magnetron sputtering at ultralow discharge voltages: Effects of defect annihilation

, 2017
Preparation of high quality transparent conductive oxide (TCO) films by sputter deposition involves an intricate balance of defect generation by the highly energetic negative oxygen ions (depending on the discharge voltage) and the concomitant ...
Ge, Fangfang, Fanping Meng, Huang, Feng, Huang,F, Feng Huang, Meng, Fanping, Yuyun Chen, Chen, Yuyun, Fangfang Ge   +8 more
core   +1 more source

Propagation dynamics of mixed-pattern solitons in strongly nonlocal nonlinear media

Results in Physics, 2019
This paper mainly investigated the propagation dynamics of the mixed-pattern solitons in strongly nonlocal nonlinear media. The propagation expression of the mixed-pattern soliton is derived, and its propagation characteristics are analyzed, including ...
Shuai Jia, Li-Min Song, Zhen-Jun Yang, Zhao-Guang Pang, Xing-Liang Li, Shu-Min Zhang   +5 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Optimized Conditions for Catalytic Chemical Vapor Deposition of Vertically Aligned Carbon Nanotubes [PDF]

Journal of Sciences, Islamic Republic of Iran, 2015
Here, we have synthesized vertically aligned carbon nanotubes (VA-CNTs), using chemical vapor deposition (CVD) method. Cobalt and ethanol are used as the catalyst and the carbon source, respectively.
M. Makenali, R. Ajeian, M. Tavakkoli, M. Nakhaee Badrabadi, S. Panahian Jand, M. Zare   +5 more
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

High-Uniformity Flat-Top Light Spot Based on a Dielectric Metasurface

Nanomaterials
With the rapid development of laser processing and infrared imaging, the demand for flat-top beams with high uniformity has become increasingly urgent.
Xinxin Pu, Wenhao Guo, Jinyao Hou, Yechuan Zhu, Xueping Sun, Shun Zhou, Weiguo Liu   +6 more
doaj   +1 more source

High-Performance All-Optical Terahertz Modulator Based on Graphene/TiO2/Si Trilayer Heterojunctions

Nanoscale Research Letters, 2019
In this paper, we demonstrate a trilayer hybrid terahertz (THz) modulator made by combining a p-type silicon (p-Si) substrate, TiO2 interlayer, and single-layer graphene. The interface between Si and TiO2 introduced a built-in electric field, which drove
Miaoqing Wei, Dainan Zhang, Yuanpeng Li, Lei Zhang, Lichuan Jin, Tianlong Wen, Feiming Bai, Huaiwu Zhang   +7 more
doaj   +1 more source