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The Ebolavirus genus contains several of the deadliest zoonotic viruses known. One of these, Bundibugyo virus (BDBV), has been the causative agent of two outbreaks of human disease that have resulted in 211 known cases with a case fatality rate of 33.6%.
Charles E. Lewis+8 more
wiley +1 more source
Essay on the Elusive Natural History of Ebola Viruses [PDF]
This chapter presents a review of what is known about the natural history of the Ebolaviruses in Central and West Africa as well as in the Philippines. All the previous hypotheses on the natural cycle of Ebolavirus are revisited.
Gonzalez, Jean-Paul+4 more
core +2 more sources
Ebola hemorrhagic fever, caused by the highly virulent RNA virus of the filoviridae family, has become one of the world's most feared pathogens. The virus induces acute fever and death, often associated with hemorrhagic symptoms in up to 90% of infected ...
Gerald Amandu Matua+2 more
doaj
Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins
Filoviruses (family Filoviridae) include five ebolaviruses and Marburg virus. These pathogens cause a rapidly progressing and severe viral disease with high mortality rates (generally 30–90%).
E. Nyakatura+9 more
semanticscholar +1 more source
The breadth of viruses in human semen [PDF]
Zika virus RNA is frequently detected in the semen of men after Zika virus infection. To learn more about persistence of viruses in genital fluids, we searched PubMed for relevant articles. We found evidence that 27 viruses, across a broad range of virus
Horby, Peter, Salam, Alex
core +2 more sources
The Role of Platelets in Viral Hemorrhagic Fevers [PDF]
Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae are all RNA viruses that can induce a coagulopathy in infected patients. While there is a paucity of information on the cause of this coagulopathy, these viruses all produce a severe ...
Cox, Dermot+2 more
core +1 more source
Ebola virus disease 2014 [PDF]
Ebola virus disease was irst described in 1976 originating from the Ebola River in the Democratic Republic of Congo. Since then, Ebola virus has become an important public health threat in Africa, and now it is of great concern worldwide due to the ...
Arellanos Soto, Daniel+4 more
core
Ebola: a holistic approach is required to achieve effective management and control. [PDF]
The current Ebola outbreak in West Africa has already caused substantial mortality and dire human and economic consequences. It continues to represent an alarming public health threat in the region and beyond and jeopardizes the provision of health care ...
Afolabi, Muhammed O+3 more
core +1 more source
Ebola Virus Disease: The Biology, Pathology, Treatments, and Advancements [PDF]
Ebola virus disease (EVD) is caused by a virulent pathogen, which is a member of the viral family Filoviridae. It is a filamentous viral particle containing a single stranded, negative RNA. It causes extreme fatal hemorrhagic fever in both humans and non-
Delgado, Eric+2 more
core +1 more source
Exploring the Pathophysiological Concepts of Ebola Virus [PDF]
The Ebola virus is a member of the filoviridae family. Five distinctive species of ebolavirus have been identified, four of which are known to cause disease in humans (Martines, Ng, Greer, Rollin, and Zaki, 2014).
Wasson, Andrew T
core +1 more source