Results 11 to 20 of about 3,142,131 (181)

The neglected continuously emerging Marburg virus disease in Africa: A global public health threat

Health Science Reports, Volume 6, Issue 11, November 2023., 2023
Abstract Background and Aim Severe viral hemorrhagic fever (VHF) is caused by Marburg virus which is a member of the Filoviridae (filovirus) family. Many Marburg virus disease (MVD) outbreaks are reported in five decades. A major notable outbreak with substantial reported cases of infections and deaths was in 2022 in Uganda.
Devang Srivastava, Lakshmi Venkata Simhachalam Kutikuppala, Pooja Shanker, Rudra Narayan Sahoo, Gurudutta Pattnaik, Rasmita Dash, Venkataramana Kandi, Azaj Ansari, Snehasish Mishra, Dhruv N. Desai, Ranjan K. Mohapatra, Ali A. Rabaan, Md. Kudrat‐E‐Zahan   +12 more
wiley   +3 more sources

Marburg virus outbreaks in Africa

Bulletin of the National Research Centre, 2023
Marburg virus disease (MVD) is a zoonotic viral hemorrhagic illness, caused by a negative sense, single-stranded RNA virus which has an envelope. The Marburg virus belongs to the genus Marburgvirus of the family Filoviridae.
Ibrahim Idris, Ridwan Olamilekan Adesola, Joanna Nicole D’Souza   +2 more
doaj   +2 more sources

γδ T Cells in Emerging Viral Infection: An Overview

Viruses, 2022
New emerging viruses belonging to the Coronaviridae, Flaviviridae, and Filoviridae families are serious threats to public health and represent a global concern.
Eleonora Cimini, Chiara Agrati
doaj   +2 more sources

Filoviruses are ancient and integrated into mammalian genomes [PDF]

BMC Evolutionary Biology, 2010
Background Hemorrhagic diseases from Ebolavirus and Marburgvirus (Filoviridae) infections can be dangerous to humans because of high fatality rates and a lack of effective treatments or vaccine.
Bruenn, Jeremy, Leach, Robert W, Taylor, Derek J   +2 more
core   +5 more sources

Factors affecting RIG-I-Like receptors activation - New research direction for viral hemorrhagic fevers

Frontiers in Immunology, 2022
Viral hemorrhagic fever (VHF) is a term referring to a group of life-threatening infections caused by several virus families (Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae).
Paulina Małkowska, Paulina Małkowska, Paulina Niedźwiedzka-Rystwej   +2 more
doaj   +2 more sources

Filovirus infections: science and innovation

Сибирский научный медицинский журнал
Epidemics of Filovirus Hemorrhagic Fevers demonstrate an increase in incidence, a reduction in the intervals between outbreaks, the emergence of a risk of infection spreading to non-endemic regions in recent years.
L. N. Aftaeva, V. L. Melnikov, A. V. Arekhina   +2 more
doaj   +2 more sources

A compendium of multi-omics data illuminating host responses to lethal human virus infections

Scientific Data
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death.
Amie J. Eisfeld, Lindsey N. Anderson, Shufang Fan, Kevin B. Walters, Peter J. Halfmann, Danielle Westhoff Smith, Larissa B. Thackray, Qing Tan, Amy C. Sims, Vineet D. Menachery, Alexandra Schäfer, Timothy P. Sheahan, Adam S. Cockrell, Kelly G. Stratton, Bobbie-Jo M. Webb-Robertson, Jennifer E. Kyle, Kristin E. Burnum-Johnson, Young-Mo Kim, Carrie D. Nicora, Zuleyma Peralta, Alhaji U. N’jai, Foday Sahr, Harm van Bakel, Michael S. Diamond, Ralph S. Baric, Thomas O. Metz, Richard D. Smith, Yoshihiro Kawaoka, Katrina M. Waters   +28 more
doaj   +2 more sources

Ebola Virus Entry: From Molecular Characterization to Drug Discovery

Viruses, 2019
Ebola Virus Disease (EVD) is one of the most lethal transmissible infections, characterized by a high fatality rate, and caused by a member of the Filoviridae family.
Cristiano Salata, Arianna Calistri, Gualtiero Alvisi, Michele Celestino, Cristina Parolin, Giorgio Palù   +5 more
doaj   +2 more sources

Distinct transcriptional responses to fatal Ebola virus infection in cynomolgus and rhesus macaques suggest species-specific immune responses

Emerging Microbes and Infections, 2021
Ebola virus (EBOV) is a negative single-stranded RNA virus within the Filoviridae family and the causative agent of Ebola virus disease (EVD). Nonhuman primates (NHPs), including cynomolgus and rhesus macaques, are considered the gold standard animal ...
Amanda N. Pinski, Kevin J. Maroney, Andrea Marzi, Ilhem Messaoudi   +3 more
doaj   +2 more sources

Evasion of the Interferon-Mediated Antiviral Response by Filoviruses [PDF]

Viruses, 2010
The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of ...
Barnes, Baron, Bradfute, Bray, Breman, Chan, Formenty, Geisbert, Georges, Haller, Harcourt, Hayes, Heymann, Jahrling, Jin, Khan, Kissling, Kudoyarova-Zubavichene, Lamb, Levy, Lin, Mahanty, Malmgaard, Mupapa, Peters, Prele, Public Health Agency of Canada, Rollin, Sanchez, Villinger, Washington B. Cárdenas, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization Global Alert and Response (GAR), Yoneyama   +41 more
core   +5 more sources