Results 31 to 40 of about 3,142,131 (181)

Luminescent reporter cells enable the identification of broad‐spectrum antivirals against emerging viruses

Journal of Medical Virology, Volume 95, Issue 11, November 2023., 2023
Abstract The emerging viruses SARS‐CoV‐2 and arenaviruses cause severe respiratory and hemorrhagic diseases, respectively. The production of infectious particles of both viruses and virus spread in tissues requires cleavage of surface glycoproteins (GPs) by host proprotein convertases (PCs).
Karin Löw, Rebecca Möller, Cora Stegmann, Miriam Becker, Laura Rehburg, Helena Obernolte, Dirk Schaudien, Lisa Oestereich, Armin Braun, Stefan Kunz, Gisa Gerold   +10 more
wiley   +1 more source

Communicating the risks of handling bats: analysing approaches used by Australian stakeholders in the context of Australian bat lyssavirus

Australian Veterinary Journal, Volume 101, Issue 11, Page 430-439, November 2023., 2023
Australian bat lyssavirus (ABLV) is a member of the Lyssavirus genus of the Rhabdoviridae family and is found in Australian bat species. It is of public health concern because of the rabies‐like syndrome it causes in humans, resulting in government health and wildlife agencies using varied communication approaches to inform targeted audiences about ...
BP Liang, K Wingett, KL Bosward, MR Taylor   +3 more
wiley   +1 more source

Molecular diagnostic and genetic characterization of highly pathogenic viruses: application during Crimean–Congo haemorrhagic fever virus outbreaks in Eastern Europe and the Middle East [PDF]

, 2012
Several haemorrhagic fevers are caused by highly pathogenic viruses that must be handled in Biosafety level 4 (BSL–4) containment. These zoonotic infections have an important impact on public health and the development of a rapid and differential ...
Avsic-Zupanc, T., Berthet, N., Caro, V., Chinikar, S., Desprès, P., Filippone, C., Gessain, A., Marianneau, P., Mollard, N., Murri, S., Tordo, N.   +10 more
core   +1 more source

The mortality, modes of infection, diagnostic tests, and treatments of Marburg virus disease: A systematic review

Health Science Reports, Volume 6, Issue 9, September 2023., 2023
Abstract Background and Aims Marburg virus (MARV) has regularly affected people since 1967 causing multiple outbreaks. There are presently no authorized therapies for the fatal Marburg virus disease (MVD), which poses an imminent risk to global public health.
Deekshitha Alla, Sai Sri Hari Paruchuri, Angad Tiwari, Sai Santhosha Mrudula Alla, Rakesh Thulaseedharan Pillai, Sandeep Kumar Reddy Bandakadi, Anju Pradeep, Dhruv Jayeshkumar Shah, Mert Sabıroğlu, Sachi Chavda, Patrick Biziyaremye   +10 more
wiley   +1 more source

Experimental Vaccines for Prevention of Marburg Hemorrhagic Fever and Animal Models for Studying Pathogenesis

Проблемы особо опасных инфекций, 2018
Marburg fever is an acute natural-focal disease characterized by severe course, hemorrhagic syndrome, high level of contagiousness and lethality. The causative agent of the disease is the RNA-containing virus belonging to the family of filoviruses ...
N. V. Volkova, E. I. Kazachinskaya, D. N. Shcherbakov   +2 more
doaj   +1 more source

Animal models for filovirus infections

Zoological Research, 2018
The family Filoviridae, which includes the genera Marburgvirus and Ebolavirus, contains some of the most pathogenic viruses in humans and non-human primates (NHPs), causing severe hemorrhagic fevers with high fatality rates.
V. Siragam, G. Wong, X. Qiu
semanticscholar   +1 more source

Predicting the combined effects of case isolation, safe funeral practices, and contact tracing during Ebola virus disease outbreaks

medRxiv, 2022
Background: The recent outbreaks of Ebola virus disease (EVD) in Uganda and the Marburg virus disease in Ghana reflect a persisting threat of Filoviridae to the global health community.
Aliou Bouba, K. Helle, K. Schneider
semanticscholar   +1 more source

Chloroquine could be used for the treatment of filoviral infections and other viral infections that emerge or emerged from viruses requiring an acidic pH for infectivity

Cell Biochemistry and Function, 2016
Viruses from the Filoviridae family, as many other virus families, require an acidic pH for successful infection and are therefore susceptible to the actions of 4‐aminoquinolines, such as chloroquine.
H. Akpovwa
semanticscholar   +1 more source

Lloviu Virus in Europe is an Emerging Disease of Concern

EcoHealth, 2022
Emerging infectious diseases pose an extreme risk for animal populations. Two current devastatingly widespread epizootics, both caused by fungal pathogens, are chytridiomycosis and white-nose syndrome. These infections are responsible for global declines
Tamás Görföl, G. Tóth, S. Boldogh, F. Jakab, G. Kemenesi   +4 more
semanticscholar   +1 more source

Containing the threat - don't forget Ebola [PDF]

, 2004
In 2000, Uganda experienced the largest outbreak of Ebola fever ever described.
Geisbert, Jonathan Cohen, Lamunu
core   +4 more sources