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Animal models for Ebola and Marburg virus infections
Ebola and Marburg hemorrhagic fevers (EHF and MHF) are caused by the Filoviridae family, Ebolavirus and Marburgvirus (ebolavirus and marburgvirus), respectively. These severe diseases have high mortality rates in humans.
E. Nakayama, M. Saijo
semanticscholar +1 more source
Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
B. Friedrich+6 more
semanticscholar +1 more source
Outbreak of Marburg hemorrhagic fever among miners in Kamwenge and Ibanda Districts, Uganda, 2007 [PDF]
Marburg hemorrhagic fever was detected among 4 miners in Ibanda District, Uganda, from June through September, 2007. Infection was likely acquired through exposure to bats or bat secretions in a mine in Kamwenge District, Uganda, and possibly human-to ...
Atek Kagirita+31 more
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Ancient viral integrations in marsupials: a potential antiviral defence
Marsupial viruses are understudied compared to their eutherian mammal counterparts, although they may pose severe threats to vulnerable marsupial populations.
Emma F. Harding+4 more
semanticscholar +1 more source
Risks Posed by Reston, the Forgotten Ebolavirus [PDF]
Out of the five members of the Ebolavirus family, four cause lifethreatening disease, whereas the fifth, Reston virus (RESTV), is nonpathogenic in humans. The reasons for this discrepancy remain unclear. In this review, we analyze the currently available
Arran Hamlet+5 more
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Filoviral haemorrhagic fevers: A threat to Zambia?
Filoviral haemorrhagic fevers (FVHF) are caused by agents belonging to Filoviridae family, Ebola and Marburg viruses. They are amongst the most lethal pathogens known to infect humans. Incidence of FVHF outbreaks are increasing, with affected number of
Katendi Changula, A.S. Mweene
doaj +1 more source
Insights into Reston virus spillovers and adaption from virus whole genome sequences. [PDF]
Reston virus (family Filoviridae) is unique among the viruses of the Ebolavirus genus in that it is considered non-pathogenic in humans, in contrast to the other members which are highly virulent.
César G Albariño+6 more
doaj +1 more source
Remdesivir for the Treatment of COVID-19: A Systematic Review of the Literature [PDF]
In March 2020, the World Health Organization declared the spread of SARS-CoV-2 a global pandemic. To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and over 99,000 deaths. Given that there is
Aly, Besma+9 more
core
The study of filovirus pathogenesis is critical for understanding the consequences of infection and for the development of strategies to ameliorate future outbreaks.
Rebecca I. Johnson+8 more
semanticscholar +1 more source
Marburg haemorrhagic fever: recent advances [PDF]
Viral hemorrhagic fevers (VHFs) are a group of etiologically diverse viral diseases unified by common underlying pathophysiology. These febrile diseases result from infection by viruses from four viral families: Arenaviridae, Bunyaviridae, Filoviridae ...
AdegborO, B, Adeola, OA
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