Persistence and Organ Tropism of Filoviruses in Farmed European Perch (Perca fluviatilis)
Journal of Fish Diseases, EarlyView.
Johanna Perschthaler +4 more
wiley +1 more source
Land Use Change and Infectious Disease Emergence
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli +6 more
wiley +1 more source
The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis [PDF]
The interferon-induced transmembrane protein (IFITM) family of proteins inhibit infection of several different enveloped viruses in cell culture by virtue of their ability to restrict entry and fusion from late endosomes.
Bradbury LE +6 more
core +2 more sources
The emergence and re-emergence of pathogens with pandemic potential has been a persistent issue throughout history. Recent decades have seen significant outbreaks of zoonotic viruses from members of the Coronaviridae, Filoviridae, Paramyxoviridae ...
Melanie M. Goens +4 more
doaj +1 more source
Borna disease virus and its role in the pathology of animals and humans
Infectious diseases that are caused by numerous pathogenic microorganisms – bacteria, viruses, protozoa or fungi – can be transmitted from patients or carriers to healthy people or animals.
A. O. Mikheev
doaj +1 more source
A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi +9 more
wiley +1 more source
A compendium of multi-omics data illuminating host responses to lethal human virus infections
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death.
Amie J. Eisfeld +28 more
doaj +1 more source
Niemann-Pick C1 (NPC1)/NPC1-like1 Chimeras Define Sequences Critical for NPC1’s Function as a Filovirus Entry Receptor [PDF]
We recently demonstrated that Niemann-Pick C1 (NPC1), a ubiquitous 13-pass cellular membrane protein involved in lysosomal cholesterol transport, is a critical entry receptor for filoviruses.
Chandran, Kartik +7 more
core +2 more sources
Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal
Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe +17 more
wiley +1 more source
Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier +4 more
wiley +1 more source

