Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 [PDF]
, 2014 In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa.
Andersen, Kristian G. +43 more
core +4 more sources
Проблемы особо опасных инфекций, 2018 Chiroptera is one of the largest in numbers orders of mammals which can take on the role of natural host and vector of various viruses, bacteria, and pathogenic fungi.
A. M. Porshakov +3 more
doaj +1 more source
Roles of VP35, VP40 and VP24 Proteins of Ebola Virus in Pathogenic and Replication Mechanisms [PDF]
, 2016 Ebola epidemic is a fatal disease due to Ebola virus belonging to Filoviridae; currently the viral evolution caused more than 50% of death worldwide. Among the eight proteins of ZEBOV, there are four structural proteins VP35, VP40, VP24, and NP, which ...
Boughribil, Said +5 more
core +2 more sources
Risk Factors for Marburg Hemorrhagic Fever, Democratic Republic of the Congo
Emerging Infectious Diseases, 2003 We conducted two antibody surveys to assess risk factors for Marburg hemorrhagic fever in an area of confirmed Marburg virus transmission in the Democratic Republic of the Congo.
Daniel G. Bausch +18 more
doaj +1 more source
Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors.
Journal of Medicinal Chemistry, 2020 Filoviridae, including Ebola (EBOV) and Marburg (MARV) viruses, are emerging pathogens that pose a serious threat to public health. No agents have been approved to treat filovirus infections, representing a major unmet medical need.
L. Cooper +12 more
semanticscholar +1 more source
Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans [PDF]
Cell RepSummary: Viral pandemics and epidemics pose a significant global threat. While macaque models of viral disease are routinely used, it remains unclear how conserved antiviral responses are between macaques and humans.
Ratnasiri K +17 more
europepmc +1 more source
Reverse genetics of Mononegavirales: How they work, new vaccines, and new cancer therapeutics. [PDF]
, 2015 The order Mononegavirales includes five families: Bornaviridae, Filoviridae, Nyamaviridae, Paramyxoviridae, and Rhabdoviridae. The genome of these viruses is one molecule of negative-sense single strand RNA coding for five to ten genes in a conserved ...
Cattaneo, Roberto +2 more
core +2 more sources
Ebola, the Negative Stranded RNA Virus [PDF]
, 2020 Ebola virus (EBV) is a deadly virus that has resulted in a number of deaths during its outbreaks in Africa in 2014–2016 and 2018–2019. This virus causes a hemorrhagic fever like other pathogenic viruses of the Filoviridae family with high mortality rate.
Ahmad, Nasir +4 more
core +2 more sources
A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection
Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi +9 more
wiley +1 more source
Re-emergence of Lloviu virus in Miniopterus schreibersii bats, Hungary, 2016
Emerging Microbes and Infections, 2018 Members of the virus family Filoviridae, such as ebola viruses and marburgviruses, cause hemorrhagic fevers associated with high mortality and are, therefore, of major public health importance worl...
G. Kemenesi +8 more
semanticscholar +1 more source