Results 71 to 80 of about 5,377 (165)

Marburg virus is nature's wake-up call: A bird's-eye view

Medicine in Microecology
Marburg virus (MARV), a member of Filoviridae family, is notorious for causing Marburg virus disease (MVD), one of the deadliest known infectious diseases. Over the past five decades, more than 15 MVD outbreaks have been reported in the African countries,
Sanjit Boora, Sulochana Kaushik, Jaya Parkash Yadav, Samander Kaushik, Dharmender Kumar   +4 more
doaj   +1 more source

A public, cross‐reactive glycoprotein epitope confounds Ebola virus serology

Journal of Medical Virology, Volume 96, Issue 10, October 2024.
Abstract Ebola disease (EBOD) in humans is a severe disease caused by at least four related viruses in the genus Orthoebolavirus, most often by the eponymous Ebola virus. Due to human‐to‐human transmission and incomplete success in treating cases despite promising therapeutic development, EBOD is a high priority in public health research.
Markus H. Kainulainen, Jessica R. Harmon, Elif Karaaslan, Jackson Kyondo, Amy Whitesell, Sam Twongyeirwe, Jason H. Malenfant, Jimmy Baluku, Aaron Kofman, Éric Bergeron, Michelle A. Waltenburg, Luke Nyakarahuka, Stephen Balinandi, Caitlin M. Cossaboom, Mary J. Choi, Trevor R. Shoemaker, Joel M. Montgomery, Christina F. Spiropoulou   +17 more
wiley   +1 more source

A meta‐analysis exploring associations between habitat degradation and Neotropical bat virus prevalence and seroprevalence

Ecography, Volume 2024, Issue 10, October 2024.
Habitat degradation can increase zoonotic disease risks by altering infection dynamics in wildlife and increasing wildlife–human interactions. Bats are an important taxonomic group to consider these effects, because they harbour many relevant zoonotic viruses and have species‐ and context‐dependent responses to degradation that could affect zoonotic ...
Alexis M. Heckley, Lauren R. Lock, Daniel J. Becker   +2 more
wiley   +1 more source

Carbon‐Based Nanomaterials for Antiviral Applications

Advanced Functional Materials, Volume 34, Issue 38, September 18, 2024.
Carbon‐based nanomaterials (CBNs), including fullerenes, carbon dots, graphene, and their derivatives, show promise as antiviral tools in the antimicrobial resistance era. They exhibit broad‐spectrum antiviral activity with a low risk of resistance development. CBNs also enhance efficacy under light exposure and support antiviral immune responses. CBNs
Ángel Serrano‐Aroca, Kazuo Takayama, Yogendra Kumar Mishra, Cesar de la Fuente‐Nunez   +3 more
wiley   +1 more source

Ebola Virus Infection: a review on the pharmacokinetic and pharmacodynamic properties of drugs considered for testing in human efficacy trials [PDF]

, 2016
International audienceThe 2014-2015 outbreak of Ebola virus disease (EVD) is the largest epidemic to date in terms of number of cases, of death and affected areas. In October 2015, no antiviral agents had proven an antiviral efficacy in patients. However
De Lamballerie, Xavier, Guedj, Jeremie, Madelain, Vincent, Mentré, France, Nguyen, Thi Huyen Tram, Olivo, Anaelle, Taburet, Anne-Marie   +6 more
core   +3 more sources

Current state of diagnostics of pathogens of viral hemorrhagic fevers using isothermal amplification method

Сибирский научный медицинский журнал
The work is an overview of the loop-mediated isothermal amplification (LAMP) method and its application to diagnostics of hemorrhagic fevers. Its objective was to briefly characterize isothermal amplification and systematize the available data on ...
E. I. Krivosheina, K. R. Belichenko, M. Yu. Kartashov, E. V. Chub   +3 more
doaj   +1 more source

Ebola virus disease: facts and fears [PDF]

, 2015
Ebola virus (EBOV) is an enveloped virus including a negative single strand genome in its virion with cylindrical/tubular morphology. EBOV is the causative agent of Ebola virus disease (EVD), which is also involved in the outbreak observed in Central ...
Karimi, A.
core  

Lyophilisation of influenza, rabies and Marburg lentiviral pseudotype viruses for the development and distribution of a neutralisation-assay based diagnostic kit [PDF]

, 2014
Pseudotype viruses (PVs) are chimeric, replication-deficient virions that mimic wild-type virus entry mechanisms and can be safely employed in neutralisation assays, bypassing the need for high biosafety requirements and performing comparably to ...
Assar, Berge, Brauburger, Capecchi, Cliquet, Cox, Croyle, Demaison, Desvaux, Edward Wright, Fellowes, Gao, Higashikawa, Jackson, Kaku, Kishishita, Loi, Lowen, Mather, Molesti, Nigel J. Temperton, Noti, Papenburg, Pear, Scott, Scott, Shin, Simon D. Scott, Stoker, Stuart T. Mather, Temperton, Temperton, Terregino, To, Tong, Tyrrell, Wei, WHO, WHO, Wilschut, Wright, Wright, Wright, Yuen, Zufferey   +44 more
core   +3 more sources

In-silico identification of novel natural drug leads against the Ebola virus VP40 protein: A promising approach for developing new antiviral therapeutics

Informatics in Medicine Unlocked
Ebola, one of the deadliest known infectious diseases, was the root of epidemics in Western Africa from 2013 to 2016. Like other deadly viruses in the family Filoviridae with a high fatality rate, this virus also causes hemorrhagic fever.
Noimul Hasan Siddiquee, Md Ifteker Hossain, Md Enamul Kabir Talukder, Syed Afnan Arefin Nirob, Md Shourav, Israt Jahan, Umme Habiba Akter Tamanna, Pinky Das, Rahima Akter, Mahmudul Hasan, Md Abdullah-Al-Mamun, Otun Saha   +11 more
doaj   +1 more source

The Role of Platelets in Viral Hemorrhagic Fevers [PDF]

, 2013
Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae are all RNA viruses that can induce a coagulopathy in infected patients. While there is a paucity of information on the cause of this coagulopathy, these viruses all produce a severe ...
Cox, Dermot, Salvato, Maria S, Zapata, Juan Carlos   +2 more
core   +1 more source