Results 71 to 80 of about 3,142,131 (181)

Ecologic and geographic distribution of filovirus disease [PDF]

, 2010
Centers for Disease Control and Prevention http://www.cdc.gov/ncidod/EID/vol10no1/03-0125.htmWe used ecologic niche modeling of outbreaks and sporadic cases of filovirus-associated hemorrhagic fever (HF) to provide a large-scale perspective on the ...
Bauer, John T., Mills, James N., Peterson, A. Townsend   +2 more
core   +4 more sources

Ebola Virus Disease: Progress So Far in the Management of the Disease [PDF]

, 2018
Ebola virus disease is one of the most deadly emerging infectious diseases in the world which causes severe haemorrhagic fever, with a mortality rate of 50–90%.
Engwa, Godwill Azeh
core   +1 more source

Survey of clinical features, pathogenesis and therapeutic options for Ebola haemorrhagic fever [PDF]

, 2015
      The genus Ebola virus first was recognized in 1976, when two outbreaks occurred in Zaire and Sudan. Ebola virus disease (EVD) is a highly contagious disease that can affect both human and nonhuman primates: Zaire ebolavirus (ZEBOV), Sudan ...
Azad, Mehdi, Fazeli, Maryam, Goudarzi, Mehdi, Seyedjavadi, Sima Sadat   +3 more
core   +2 more sources

Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39

British Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier, Viktoria M. S. Kjær, Stephen Griffin, Birthe B. Kragelund, Mette M. Rosenkilde   +4 more
wiley   +1 more source

RNA binding motif 4 inhibits the replication of ebolavirus by directly targeting 3′-leader region of genomic RNA

Emerging Microbes and Infections
Ebola virus (EBOV) belongs to Filoviridae family possessing single-stranded negative-sense RNA genome, which is a serious threat to human health. Nowadays, no therapeutics have been proven to be successful in efficiently decreasing the mortality rate ...
Linjin Fan, Yulong Wang, Hongxin Huang, Zequn Wang, Chudan Liang, Xiaofeng Yang, Pengfei Ye, Jingyan Lin, Wendi Shi, Yuandong Zhou, Huijun Yan, Zhenyu Long, Zhongyi Wang, Linna Liu, Jun Qian   +14 more
semanticscholar   +1 more source

A public, cross‐reactive glycoprotein epitope confounds Ebola virus serology

Journal of Medical Virology, Volume 96, Issue 10, October 2024.
Abstract Ebola disease (EBOD) in humans is a severe disease caused by at least four related viruses in the genus Orthoebolavirus, most often by the eponymous Ebola virus. Due to human‐to‐human transmission and incomplete success in treating cases despite promising therapeutic development, EBOD is a high priority in public health research.
Markus H. Kainulainen, Jessica R. Harmon, Elif Karaaslan, Jackson Kyondo, Amy Whitesell, Sam Twongyeirwe, Jason H. Malenfant, Jimmy Baluku, Aaron Kofman, Éric Bergeron, Michelle A. Waltenburg, Luke Nyakarahuka, Stephen Balinandi, Caitlin M. Cossaboom, Mary J. Choi, Trevor R. Shoemaker, Joel M. Montgomery, Christina F. Spiropoulou   +17 more
wiley   +1 more source

Ebola virus disease: past, present and future

Asian Pacific Journal of Tropical Biomedicine, 2015
Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%) accompanying with the disease. Ebola haemorrhagic fever (EHF) is an infectious disease of animal that can be transmitted to both human and ...
Harish Rajak, Deepak Kumar Jain, Avineesh Singh, Ajay Kumar Sharma, Anshuman Dixit   +4 more
doaj   +1 more source

A meta‐analysis exploring associations between habitat degradation and Neotropical bat virus prevalence and seroprevalence

Ecography, Volume 2024, Issue 10, October 2024.
Habitat degradation can increase zoonotic disease risks by altering infection dynamics in wildlife and increasing wildlife–human interactions. Bats are an important taxonomic group to consider these effects, because they harbour many relevant zoonotic viruses and have species‐ and context‐dependent responses to degradation that could affect zoonotic ...
Alexis M. Heckley, Lauren R. Lock, Daniel J. Becker   +2 more
wiley   +1 more source

Some Opportunities that the Covid-19 Pandemic has Shown us

Otolaryngology Open Access Journal
Emerging or re-emerging viral infections significantly affect human health. In recent decades, we have observed the emergence of new diseases in different geographical areas caused by a large number of highly pathogenic viruses belonging to the families ...
Toma Avramov
semanticscholar   +1 more source

Carbon‐Based Nanomaterials for Antiviral Applications

Advanced Functional Materials, Volume 34, Issue 38, September 18, 2024.
Carbon‐based nanomaterials (CBNs), including fullerenes, carbon dots, graphene, and their derivatives, show promise as antiviral tools in the antimicrobial resistance era. They exhibit broad‐spectrum antiviral activity with a low risk of resistance development. CBNs also enhance efficacy under light exposure and support antiviral immune responses. CBNs
Ángel Serrano‐Aroca, Kazuo Takayama, Yogendra Kumar Mishra, Cesar de la Fuente‐Nunez   +3 more
wiley   +1 more source