Results 51 to 60 of about 130,053 (265)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Perspective-based search: a new paradigm for bursting the information bubble

FACETS, 2019
Nowadays, individuals heavily rely on search engines for seeking information. The presence of information bubbles (filter bubbles and echo chambers) can threaten the effectiveness of these systems in providing unbiased information and damage healthy ...
Shayan A. Tabrizi, Azadeh Shakery
doaj   +1 more source

Filter Bubbles and Echo Chambers: Pre-digital Origins and Elements of Novelty - Reflections from a Media Education Perspective

Formazione & Insegnamento, 2022
As pointed out by Edgar Morin, a crucial issue for contemporary pedagogy is to understand how to support the new generations in acquiring the ability to orient themselves in the abundance of information made available by digital technologies.
Pietro Corazza
doaj   +1 more source

The Effect of Absorption Systems on Cosmic Reionization [PDF]

, 2012
We use large-scale simulations to investigate the morphology of reionization during the final, overlap phase. Our method uses an efficient three-dimensional smoothing technique which takes into account the finite mean free path due to absorption systems,
Abel, Abel, Alvarez, Busha, Das, Furlanetto, Gnedin, Gnedin, Haiman, Iliev, Komatsu, Lidz, Marcelo A. Alvarez, McQuinn, McQuinn, Mesinger, Mesinger, Miralda-Escudé, Prochaska, Reichardt, Shin, Songaila, Tom Abel, Trac, Zahn, Zahn   +25 more
core   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Baryon number segregation at the end of the cosmological quark-hadron transition [PDF]

, 1996
One of the most interesting questions regarding a possible first order cosmological quark--hadron phase transition concerns the final fate of the baryon number contained within the disconnected quark regions at the end of the transition.
A. Goyal, B. Cheng, C. Alcock, C. Alcock, D. Potter, E. S. Oran, E. Witten, G. M. Fuller, H. Kurki-Suonio, J. C. Miller, J. C. Miller, J. C. Miller, J. H. Applegate, J. Ignatius, J. Ignatius, K. Jedamzik, K. Kajantie, K. Sumiyoshi, K. Sumiyoshi, L. Rezzolla, L. Rezzolla, L. Rezzzolla, Luciano Rezzolla, M. B. Christiansen, R. A. Malaney, S. A. Bonometto   +25 more
core   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

A Multi-Epoch HST Study of the Herbig-Haro Flow from XZ Tauri

, 2008
We present nine epochs of Hubble Space Telescope optical imaging of the bipolar outflow from the pre-main sequence binary XZ Tauri. Our data monitors the system from 1995-2005 and includes emission line images of the flow. The northern lobe appears to be
Brown, Burrows, Carl L. Gardner, Gilliland, Hartigan, Hester, J. Jeff Hester, John E. Krist, Karl R. Stapelfeldt, Kevin Healy, Krist, Krist, Krist, Moriarty-Schieven, Mundt, Pavlovsky, Reipurth, Schmutzler, Shu, Steven J. Dwyer, Watson, Welch, White   +22 more
core   +1 more source

Breaking the filter bubble: democracy and design [PDF]

Ethics and Information Technology, 2015
It has been argued that the Internet and social media increase the number of available viewpoints, perspectives, ideas and opinions available, leading to a very diverse pool of information. However, critics have argued that algorithms used by search engines, social networking platforms and other large online intermediaries actually decrease information
Bozdag, E. (author), Van den Hoven, M.J. (author)   +1 more
openaire   +3 more sources

Current Tracking Adaptive Control of Brushless DC Motors

International Journal of Adaptive Control and Signal Processing, EarlyView.
In this paper, the current tracking for Brushless Direct Current motors is approached considering uncertainty in the parameters of the motor's model. An adaptive control scheme to compensate electrical parameters uncertainty is proposed without requiring any knowledge of the mechanical parameters.
Fernanda Ramos‐García, Axel Coronado‐Andrade, Gerardo Espinosa‐Pérez, Luis Alvarez‐Icaza   +3 more
wiley   +1 more source