Results 61 to 70 of about 23,202,561 (250)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Elucidating the role of ferrous ion cocatalyst in enhancing dilute acid pretreatment of lignocellulosic biomass

Biotechnology for Biofuels, 2011
Background Recently developed iron cocatalyst enhancement of dilute acid pretreatment of biomass is a promising approach for enhancing sugar release from recalcitrant lignocellulosic biomass.
Wei Hui, Donohoe Bryon S, Vinzant Todd B, Ciesielski Peter N, Wang Wei, Gedvilas Lynn M, Zeng Yining, Johnson David K, Ding Shi-You, Himmel Michael E, Tucker Melvin P   +10 more
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

A Fast Algorithm for the High Order Linear and Nonlinear Gaussian Regression filter [PDF]

, 2009
In this paper, the general model of the Gaussian regression filter, including both the linear and nonlinear filter of zeroth, second order, has been reviewed.
Zeng, Wenhan, Blunt, Liam, Jiang, Xiang, Xiao, Shaojun, Scott, Paul J.   +4 more
core   +3 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

The use of filter paper plasticized with polyvinyl alcohol-glutaraldehyde in ELISA

Brazilian Journal of Medical and Biological Research, 2000
F1-antigen purified from Yersinia pestis was covalently linked to 5-mm diameter filter paper discs plasticized with polyvinyl alcohol-glutaraldehyde. These discs were used both for ELISA and dot-ELISA for the detection of anti-F1 IgG in rabbits. The best
G.H.T.S. Barbosa, E.M. Santana, A.M.P. Almeida, A.M. Araujo, O. Fatibello-Filho, L.B. Carvalho Jr.   +5 more
doaj   +1 more source

The Content and Reporting Completeness of Physical Therapist–Led Interventions for Glenohumeral Osteoarthritis: A Systematic Review

Arthritis Care &Research, EarlyView.
Objective This study synthesized the content and reporting completeness of published physical therapist–led interventions for glenohumeral osteoarthritis (GHOA). Methods This systematic review undertook electronic database searches in PubMed, EMBASE, Cochrane, CINAHL, and PEDro (until June 2025) for any peer‐reviewed articles or studies describing ...
Daha G. Muhammad, Nadine E. Foster, Mickylle Pelaez, Karina O'Leary, Ilana N. Ackerman, Jonathan G. Quicke   +5 more
wiley   +1 more source

Comparison of the recovery of PCR-detectable porcine epidemic diarrhea virus and porcine reproductive and respiratory syndrome virus from filter papers under laboratory conditions

Frontiers in Cellular and Infection Microbiology
IntroductionThe need for cost effective surveillance of emerging human and veterinary pathogens has triggered a resurgence in research on environmental sampling methods, a process in which filter paper could play a role.
Betsy Armenta-Leyva, Berenice Munguía-Ramírez, Danyang Zhang, Jianqiang Zhang, Rolf Rauh, Luis G. Giménez-Lirola, Jeffrey J. Zimmerman   +6 more
doaj   +1 more source