Results 121 to 130 of about 957,847 (295)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A NOVEL APPROACH FOR DENOISING ELECTROCARDIOGRAM SIGNAL USING HYBRID TECHNIQUE [PDF]

open access: yesJournal of Engineering Science and Technology, 2017
One of the core concerns in the area of Biomedical Signal Processing has been the extraction of pure cardiologic indices from noisy measurements.
HARJEET KAUR, RAJNI
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Systolic VLSI for Kalman filters [PDF]

open access: yes
A novel two-dimensional parallel computing method for real-time Kalman filtering is presented. The mathematical formulation of a Kalman filter algorithm is rearranged to be the type of Faddeev algorithm for generalizing signal processing.
Chang, J. J., Yeh, H.-G.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

NONLINEAR AVERAGING FILTER WITH HYPERBOLIC WEIGHTS

open access: yesВестник Кемеровского государственного университета, 2013
The algorithm of a digital averaging filter, using hyperbolic weightsfor input values of the signal, is suggested. The results of digital modeling of the given filter are shown when processing monochrome images.
V. A. Tolstunov, Yu. V. Shlyndova
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Signal Processing of Control and Protection for Traction ConverterBased on Butterworth Filter

open access: yes机车电传动, 2016
Aiming at the problems of electric locomotive traction converters affected by the bad application environment andthe control strategy, which brought high frequency harmonic for sampling signal of control and protection and affected the controlperformance
ZHENG Yong, HUANG Qing, LI Xueming
doaj  

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