Results 121 to 130 of about 957,847 (295)
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A NOVEL APPROACH FOR DENOISING ELECTROCARDIOGRAM SIGNAL USING HYBRID TECHNIQUE [PDF]
One of the core concerns in the area of Biomedical Signal Processing has been the extraction of pure cardiologic indices from noisy measurements.
HARJEET KAUR, RAJNI
doaj
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Systolic VLSI for Kalman filters [PDF]
A novel two-dimensional parallel computing method for real-time Kalman filtering is presented. The mathematical formulation of a Kalman filter algorithm is rearranged to be the type of Faddeev algorithm for generalizing signal processing.
Chang, J. J., Yeh, H.-G.
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
NONLINEAR AVERAGING FILTER WITH HYPERBOLIC WEIGHTS
The algorithm of a digital averaging filter, using hyperbolic weightsfor input values of the signal, is suggested. The results of digital modeling of the given filter are shown when processing monochrome images.
V. A. Tolstunov, Yu. V. Shlyndova
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Signal Processing of Control and Protection for Traction ConverterBased on Butterworth Filter
Aiming at the problems of electric locomotive traction converters affected by the bad application environment andthe control strategy, which brought high frequency harmonic for sampling signal of control and protection and affected the controlperformance
ZHENG Yong, HUANG Qing, LI Xueming
doaj

