Results 41 to 50 of about 260,245 (315)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Development of Electrocardiograph Monitoring System

MATEC Web of Conferences, 2018
Electrocardiograph (ECG) monitoring system is one of the diagnostic tools which can help in reduce the risk of heart attack. A cardiologist may be able to determine heart condition from the ECG signal that recorded from subject. The purpose was to design
Rosli Khairul Affendi, Omar Mohd. Hafizi, Hasan Ahmad Fariz, Musa Khairil Syahmi, Fadzil Mohd Fairuz Muhamad, Neu Shu Hwei   +5 more
doaj   +1 more source

Performance of Reconstruction Algorithm Based on Sub-Nyquist Bandpass Sampling in the Pulse Position Modulation-Ultra Wide Band System

Leida xuebao, 2015
The signal reconstruction algorithm with sub-Nyquist bandpass sampling in Pulse Position Modulation-Ultra Wide Band (PPM-UWB) signal processing is analyzed based on PPM-UWB signal demodulation.
Zou Ning, Xu Zheng-guang, Ran Jian-hua, Li Chao-yang   +3 more
doaj   +1 more source

A New Denoising Method for Underwater Acoustic Signal

IEEE Access, 2020
In recent years, the rapid development of marine science has put forward higher and higher requirements for the processing of ship-radiated noise signal.
Hong Yang, Lulu Li, Guohui Li
doaj   +1 more source

ECG Signals Processing using Adaptive Linear Filters [PDF]

International Journal of Trend in Scientific Research and Development, 2017
Electrocardiogram ECG signal is the electrical recording of heart activity. The Electrocardiogram ECG reflects the activities and the attributes of the human heart and reveals very important hidden information. The information is extracted by means of ECG signal analysis to gain insights that are very crucial in explaining and identifying various ...
Ms. Chhavi Saxena, Ms. Chhavi Saxena, Dr. Hemant Gupta   +2 more
openaire   +3 more sources

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Graph signal processing: Filter design and spectral statistics [PDF]

2017 IEEE 7th International Workshop on Computational Advances in Multi-Sensor Adaptive Processing (CAMSAP), 2017
2017 IEEE International Workshop on Computational Advances in Multi-Sensor Adaptive Processing (CAMSAP 2017)
Stephen Kruzick, José M. F. Moura
openaire   +3 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Generalized Selection Weighted Vector Filters

EURASIP Journal on Advances in Signal Processing, 2004
This paper introduces a class of nonlinear multichannel filters capable of removing impulsive noise in color images. The here-proposed generalized selection weighted vector filter class constitutes a powerful filtering framework for multichannel signal ...
Smolka Bogdan, Lukac Rastislav, Plataniotis Konstantinos N, Venetsanopoulos Anastasios N   +3 more
doaj   +1 more source