Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Two-Signal Set and Adaptive Spectral Decomposition Algorithm for Estimating the Phase Velocity of Dispersive Lamb Wave Mode. [PDF]
Draudvilienė L +3 more
europepmc +1 more source
Denoising Techniques Based on the Multiresolution Representation [PDF]
So far, considerable research efforts have been invested in the are of using statistical methods for image processing purposes yielding to a significant amount of models that aim to improve as much as possible the still existing and currently used ...
Viorica STEFANESCU +3 more
core +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Air-Coupled Ultrasonic Detection of Surface Roughening and Ink Wettability. [PDF]
Li G.
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
High-Precision Laser Time-Frequency Synchronization in Space Based on an Improved Kalman Filtering Method. [PDF]
Sun B, Wang X, Sun Z, Zheng F.
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Adaptive graph signal processing for robust multimodal fusion with dynamic semantic alignment. [PDF]
Karthikeya KV +4 more
europepmc +1 more source
Application of Pattern Filtering Method in Cross-hole Tomography Signal Processing
Xu Liu, Miaorong Lv
openaire +1 more source

