Results 211 to 220 of about 74,195 (239)

Presence of bacterial DNA in synovial fluid from the temporomandibular joint in patients with temporomandibular joint disorders. [PDF]

Front Oral Health
Bazsefidpay N, Ulmner M, Damdimopoulos A, Lund B.   +3 more
europepmc   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Hypotony following the use of topical carbonic anhydrase inhibitors in glaucoma patients: a case report and review of literature. [PDF]

Int J Surg Case Rep
AlTariqi SM, Halawani MA, AlOtaiby ND.
europepmc   +1 more source

Rhythmic suture movement on gonioscopy after penetrating canaloplasty: a case report. [PDF]

BMC Ophthalmol
Liu S, Wu Z, Yu P, Zeng L.
europepmc   +1 more source

Cataract surgery in the context of age-related macular degeneration: challenges and considerations. [PDF]

J Cataract Refract Surg
Zarei-Ghanavati S, Motamed Shariati M, Hadi Y, Khazaei S, Yoo SH.   +4 more
europepmc   +1 more source

Targeting CRBN With Thalidomide Suppresses Fibrosis After Glaucoma Drainage Surgery Through NF-κB Pathway Inhibition. [PDF]

Invest Ophthalmol Vis Sci
Wang L, Li H, Xiong L, Sun C, Wang J.
europepmc   +1 more source

Development and Validation of a Machine Learning Model for Predicting Serum Creatinine-Defined Acute Kidney Injury in Older Adults After Cardiac Surgery. [PDF]

Clin Interv Aging
Fu Y, Qian J, Zhang Y, Ji F.
europepmc   +1 more source

Excimer Laser filtering surgery

, 1994
TRAVERSO, CARLO, Corazza M, Murialdo U.
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