Results 51 to 60 of about 633,915 (269)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microscopy assisted fabrication of a hydrogel-based microfluidic filter [PDF]

Journal of the European Optical Society-Rapid Publications, 2015
A porous filter is fabricated directly inside a microfluidic circuit using a photoreticulable hydrogel. The filter could be used for separation of cells from blood, removal of particles or solutes, such as proteins, in microdialysis and microfiltering ...
Caliò A., Leng J., Decock J., De Stefano L., Salmon J. B.   +4 more
doaj   +1 more source

DTM-Based Filtrations [PDF]

, 2020
Despite strong stability properties, the persistent homology of filtrations classically used in Topological Data Analysis, such as, e.g. the Cech or Vietoris-Rips filtrations, are very sensitive to the presence of outliers in the data from which they are computed.
Anai, Hirokazu, Chazal, Frédéric, Glisse, Marc, Ike, Yuichi, Inakoshi, Hiroya, Tinarrage, Raphaël, Umeda, Yuhei   +6 more
openaire   +6 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Electrostatic separator of cannabis trichomes: an innovative approach to extraction

Journal of Cannabis Research
Background Efficient separation of trichomes from plant material is critical for producing high-quality cannabis extracts. Traditional methods of separation, such as wet and dry fractionation, use the difference in mechanical properties (size, density ...
Charles MacGowan, Alex Martynenko
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Research on the application of magnetic separation technology for the removal of black powder in natural gas pipelines

You-qi chuyun
ObjectiveBlack powder, primarily composed of magnetic corrosion products, accumulates in natural gas pipelines, causing various issues when its concentrations exceed specific limits, including frequent blockages of filter elements and abnormal shutdowns ...
Hongwei YANG, Tianyu ZHANG, Fang LIU, Zhen LIU, Junxian CHEN, Wengang YANG   +5 more
doaj   +1 more source

Filtration Performance of Dual-layer Filter Paper with Fibrillated Nanofibers

BioResources, 2016
Filter paper can be dramatically improved by the slip-flow effect and the huge specific surface area of nanofibers. Nanofibers can provide significant improvement in filtration efficiency with a relatively small reduction in permeability.
Yunzhen Yao, Min Tang, Tian Yu, Yun Liang, Jian Hu   +4 more
doaj   +1 more source