Results 51 to 60 of about 290,900 (257)

On V-filtration, Hodge filtration and Fourier transform

open access: yesSelecta Mathematica, 2023
52 pages. Comments are welcome.
Chen, Qianyu, Dirks, Bradley
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Plasma Filtration

open access: yesAnnals of the Academy of Medicine, Singapore, 2005
Therapeutic plasma exchange (TPE) or plasmapheresis involves the separation of plasma from whole blood. In so doing, plasma-borne humoral disease mediators are removed from the body. This can attenuate the course and severity of the underlying disease.
H K, Tan, G, Hart
openaire   +2 more sources

Simulation d’une filtration liquide en canal poreux fermé à une extrémité avec prise en compte de la formation du dépôt [PDF]

open access: yes, 2009
La formation d’un dépôt de filtration ainsi que les performances de filtration associées ont été étudiées par CFD en utilisant un maillage mobile.
CABASSUD, Corinne   +3 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Comparative Analysis of Anion Exchange Membrane Adsorbers for Endotoxin Removal During Ultrafiltration and Diafiltration Buffer Preparation

open access: yesEngineering in Life Sciences
During the manufacturing of drug substances (DS), endotoxins are a commonly monitored contaminant and checked to ensure the safety and quality of the final product.
Sven Heimann   +3 more
doaj   +1 more source

Historical winter records of the Thick-billed Parrot (Rhynchopsitta pachyrhyncha) in Chihuahua

open access: yesHuitzil
The migration patterns of the Thick-billed Parrot (Rhynchopsitta pachyrhyncha) remain poorly known. The species usually migrates to the southern Sierra Madre Occidental for the winter, and only rarely occurs in Chihuahua during that season.
Benjamin E. Leese
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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