FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Changes in Glomerular Filtration Rate in Transgender Individuals Receiving Hormone Therapy: A Longitudinal Study. [PDF]
Clin Med Insights Endocrinol DiabetesAlfonso Vergel DC +4 more
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
, 2012 Uric acid has both antioxidant and oxidant properties, is excreted by the kidney and is associated with development of kidney disease. Albumin, another antioxidant is also excreted by the kidney in some renal diseases.
Ruven, Henk +6 more
core +1 more source
Correction: Progression of the estimated glomerular filtration rate in asphyxiated neonates undergoing therapeutic hypothermia during the first 10 days of life. [PDF]
Pediatr NephrolAllegaert K +5 more
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Investigation of skin formation during filtration of micro crystalline cellulose
, 2013 Separating solids from liquids through filtration is an important unit operation employed in a wide range of industrial sectors. It is vital that accurate and applicable models are employed when designing industrial sized filters.
Mattsson, Tuve, +2 more
core
Glomerular filtration rate estimation in nephrotic patients: creatinine and/or cystatin-C-based equations, or none of them? [PDF]
Clin Kidney JCarrara F +12 more
europepmc +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Measuring or estimating glomerular filtration rate in potential kidney donors: a comparative study. [PDF]
Clin Kidney JGama RM +4 more
europepmc +1 more source