Results 71 to 80 of about 7,873 (297)

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

Maritime and Marine Historic Environment Research Framework: the Neolithic and Early Bronze Age

open access: yes, 2010
Maritime themes have long been established in both Neolithic and Early Bronze Age research in England. From Crawford’s (1912) identification of the western seaways as a critical conduit for prehistoric communication, through Childe’s (1946, 36 ...
Van-de-Noort, Robert, Sturt, Fraser
core  

Crops and food choices at the Late Bronze Age city of Hala Sultan Tekke

open access: yes, 2021
The Late Bronze Age city of Hala Sultan Tekke (HST) is located on the south-eastern coast of Cyprus, c. 7 km south of modern-day Larnaca. The most recent excavations revealed four new city quarters (CQ1–4), where domestic and industrial activities took ...
Kofel, Dominika   +7 more
core   +1 more source

From Materials to Medical Images: Translating Perovskite‐Based X‐Ray Detectors Toward Clinical Imaging

open access: yesAdvanced Science, EarlyView.
This review examines perovskite‐based X‐ray detectors from a materials‐to‐medical‐images perspective. Recent progress in perovskite‐based X‐ray detectors is discussed with emphasis on their relevance to clinical imaging. The key barriers to clinical implementation are analyzed.
Sibin Wang   +8 more
wiley   +1 more source

Kınık Höyük from the Middle Bronze Age to the Roman period: preliminary report on the excavation at the Lower Town 2023-2024

open access: yesAsia Anteriore Antica
This article presents the second preliminary report on the excavations conducted in the Lower Town (Area D) of Kınık Höyük, located in the Bor Plain of southern Cappadocia. Recent fieldwork (2023–2025) has significantly refined the stratigraphic sequence
Marina Pucci   +12 more
doaj   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

open access: yesAdvanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung   +39 more
wiley   +1 more source

Net-Impressed Pottery of Voznesenskoye I Settlement: from the late bronze age to the early iron age

open access: yesАрхеология евразийских степей
The article introduces into scientific discourse the materials obtained during 2020 and 2022 excavations of the Voznesenskoye I settlement, a site of a multiple settling located in the surroundings of Lake Galichskoye.
Aleksandr V. Novikov
doaj   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

open access: yesAdvanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie   +20 more
wiley   +1 more source

Le Bronze moyen et le début du Bronze final dans le sud du Bassin parisien

open access: yes, 2017
International audienceIn this paper we aim to take a new look at human occupation of the south of the Paris basin during the Middle Bronze Age and the beginning of the Late Bronze Age.
Riquier, Vincent   +4 more
core  

Home - About - Disclaimer - Privacy