Results 71 to 80 of about 139,236 (284)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Literatura higienista en La Rioja a finales del siglo XIX

open access: yes, 1999
Ya desde el siglo XVIII se venía notando la necesidad de abordar la cuestión higiénica, incluso el Estado debió asumir y plantear la necesidad de una política higienista.
Delgado Idarreta, José Miguel [0000-0002-9183-8209]   +1 more
core  

Archivos Finales

open access: yes, 2018
Este documento contiene en texto completo el articulo Archivos Finales publicado en Desafíos; Vol. 25, Núm.
Desafíos, Revista
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conclusiones finales

open access: yesArquitecturas del Sur, 2005
En el desarrollo de la arquitectura moderna en el sur de Chile se distingue dos etapas: la primera, desde la década de 1930 hasta el terremoto de 1960 o de la primera modernidad, en que se introducen y desarrollan los modelos aportados por el movimiento ...
Gonzalo Cerda Brintrup   +5 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Recomendaciones finales

open access: yesTrans-pasando Fronteras, 2012
Presentación de los resúmenes en inglés (abstract) e instrucciones para los autores.
Revista Trans-pasando Fronteras
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Manual metodológico y reglamentario para la elaboración de proyectos y trabajos finales de carrera [PDF]

open access: yes, 2018
En este documento se establecen aspectos, metodológicos y normativos, mínimos para que los estudiantes de las distintas Ingenierías puedan llevar a cabo con éxito el proceso de confección de sus Proyectos y consecuentes Trabajos Finales de Carrera ...
Broz, Diego Ricardo
core  

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