Results 61 to 70 of about 123,033 (221)

Topology‐Driven X‐Shaped DNA as a cGAS Stimulator to Promote Dendritic Cell Activation and Antitumor Vaccine Efficacy

Advanced Science, EarlyView.
X‐shaped DNA promotes multivalent cGAS assembly and enhances cGAS‐STING signaling. When conjugated with antigenic peptides, the resulting X‐DNA‐based peptide vaccine promotes dendritic cell activation, antigen presentation, and antitumor T‐cell responses.
Jiabei Li, Xuan Wang, Dali Wei, Zhejie Chen, Ziyi Wang, Qing Yu, Yu Yang, Shengpeng Wang   +7 more
wiley   +1 more source

MAGI3 Acts as an Intestinal Epithelial Gatekeeper in Inflammation‐Associated Colorectal Cancer by Suppressing the STAT3‐CCL2 Axis and TAM‐Mediated Immunosuppression

Advanced Science, EarlyView.
Our study identifies MAGI3 as an intestinal epithelial gatekeeper that restrains inflammation‐associated colorectal tumorigenesis but is itself suppressed under highly inflammatory conditions. MAGI3 deficiency activates the STAT3‐CCL2 signaling, thereby promoting TAM‐mediated immunosuppression and inflammation‐associated colorectal tumor progression ...
Yumeng Yang, Zhigang Bai, Haibo Wang, Yu Guo, Yan Zhang, Meihan Hu, Shuaikang Fan, Ran Song, Tongmei Zhang, Mengqi Deng, Xiaomei Yang, Zhongtao Zhang, Junqi He   +12 more
wiley   +1 more source

Acord de col·laboració entre Barcelona d'Infraestructures Municipals i 22@BCN, per a la prestació de serveis relatius a la gestió econòmica- administrativa i de contractació 22@BCN

, 2010
Aprovat pel conseller delegat de Barcelona d'Infraestructures Municipals, S.A. i pel gerent de 22@bcn, S.A. el 26-11-2010Annex 1.
Barcelona d'Infraestructures Municipals, S.A., 22@bcn, S.A.   +1 more
core   +1 more source

A CT Lesion Foundation Model for Non‐Invasive Assessment of Hepatocellular Carcinoma Aggressiveness and Prediction of Recurrence Risk

Advanced Science, EarlyView.
A computed tomography lesion foundation model, built by sequential self‐supervised pretraining on generic and hepatocellular carcinoma‐specific lesion images, non‐invasively assesses microvascular invasion and pathological grade from contrast‐enhanced CT and stratifies postoperative recurrence risk.
Wei Xia, Zhehan Shen, Mengsi Li, Jianxin Lu, Ji Xia, Yang Cheng, Wenzheng Li, Shunjie Dong, Lin Deng, Ruokun Li   +9 more
wiley   +1 more source

Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses

Advanced Science, EarlyView.
Circulating polyethylene microplastic burden is positively associated with heightened ADHD symptom severity and systemic redox‐inflammatory imbalance in children. Mechanistic investigation in a developmental co‐exposure mouse model further demonstrates that microplastics aggravate ADHD‐like behaviors, dopaminergic dysregulation, and oxidative ...
Yufan Luo, Ruijin Xie, Hua Xu, Xue Xiao, Wei Xiao, Qiyang Pan, Shengjie Xu, Li Liu, Zeliang Xiao, Yue Zhou, Chenyu Sun, Yu Wu, Yueying Liu   +12 more
wiley   +1 more source

Development‐Informed Microsphere Assemblies Enable Spatiotemporally Programmed Bone–Vascular Organoid‐Like Constructs for Large Bone Defect Repair

Advanced Science, EarlyView.
Single‐cell‐guided prioritization of BMP4 and VEGFA is combined with temporally programmed BMSCs and a Matrigel‐free GelMA/PEO/bioactive‐glass assembled‐microsphere matrix to generate bone–vascular organoid‐like constructs. The platform coordinates osteogenic differentiation, endothelial activation, vascular‐like microchannel formation, and ...
Renhao Ni, Xinyi Shi, Tong Zhu, Guanrong Li, Lei Chang, Shengtao Li, Jingyi Chi, Chen Shi, Zeming Hu, Rong Xu, Yingchun Zhu, Yang Luo, Yichen Chen, Fan Yang, Yabin Zhu   +14 more
wiley   +1 more source

Instruccions de contractació adaptades al Decret Llei 3/2016 de 31 de maig de mesures urgents en matèria de contractació pública [PDF]

, 2016
Aprovades pel Consell d'Administració de Barcelona d'Infraestructures Municipals el 15-11 ...
Barcelona d'Infraestructures Municipals, S.A.
core   +1 more source

Towards Ideal Electron‐Transporting Transistor Characteristics in Polymer Semiconductors in Ambient Air

Advanced Electronic Materials, EarlyView.
We report a coexistence of a reliability factor of 90% and high electron mobility of 0.6 cm2 V−1 s−1 in FBDPPV‐based n‐type polymer field‐effect transistors. Efficient electron transport in this rigid, coplanar, distortion‐free polymer that induces high mobility and ideal transistor behaviors is supported by efficient intrachain transport and limited ...
Hio‐Ieng Un, Miao Xiong, Yang Lu, Chi‐Yuan Yang, Tian‐Yu Zhang, Ze‐Fan Yao, Jie‐Yu Wang, Jian Pei   +7 more
wiley   +1 more source

Deforestation and Efficiency: Insights From Forest Transition in the Brazilian Cerrado

Agribusiness, EarlyView.
ABSTRACT This paper estimates technical efficiency (TE) and environmental efficiency (EE) of agricultural production at the municipal level of the Brazilian Cerrado in 2006 and 2017, and investigates their underlying mechanisms in relation to forest transition theory.
Ricardo Muniz Simões, Cassiano Bragagnolo, Humberto Francisco Silva Spolador   +2 more
wiley   +1 more source

Annuaire général des finances.

"Publié d'après les documents officiels, sous les auspices du Ministère des finances." (varies slightly)Mode of access: Internet.Superseded by: France. Ministère de l'économie et des finances.
France. Ministère des finances.
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