Results 21 to 30 of about 562,884 (198)

Universities and enterprise education: responding to the challenges of the new era [PDF]

, 2010
Purpose The article suggests that the international financial and economic crisis in 2008 produced a new economic era with significant implications for enterprise and entrepreneurship education. It explores: 1.
Rae, David
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A theory-grounded framework of Open Source Software adoption in SMEs [PDF]

, 2011
This is a post-peer-review, pre-copyedit version of an article published in European Journal of Information Systems. The definitive publisher-authenticated version Macredie, RD and Mijinyawa, K (2011), "A theory-grounded framework of Open Source Software
Agarwal R, Benbasat I, Eisenhardt KM, Fishbein M, Kabiru Mijinyawa, Kwan SK, Lincoln YS, Mayring P, Miles MB, Overby EM, Patton MQ, Robert D Macredie, Rogers EM, Rogers EM, Venkatesh V, Yin RK, Yin RK   +16 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Theories for influencer identification in complex networks

, 2018
In social and biological systems, the structural heterogeneity of interaction networks gives rise to the emergence of a small set of influential nodes, or influencers, in a series of dynamical processes.
A Guggiola, A Zeng, Alfredo Braunstein, B Min, B Min, B Viswanath, D Kempe, D Liben-Nowell, D Rybski, D Stauffer, D. Centola, DJ Watts, DJ Watts, Duncan S. Callaway, Ed Bullmore, EM Rogers, F Altarelli, F Morone, F Morone, F Morone, F Radicchi, G Lawyer, G Sabidussi, GL Nemhauser, H Kwak, HW Hethcote, J Kleinberg, J Leskovec, J Leskovec, JG Restrepo, K Klemm, K Roth, KI Hashimoto, L Katz, L Lü, L Lü, L Lü, L Muchnik, L. K. Gallos, Linton C. Freeman, M Kitsak, M Mézard, M Ramos, M Richardson, ME Newman, ME Newman, MS Granovetter, N. Eagle, Phillip Bonacich, R Pastor-Satorras, R Pastor-Satorras, Reuven Cohen, RM Karp, Réka Albert, S Luo, S Mugisha, S Pei, S Pei, S Pei, S Pei, S Pei, S Tang, S Yan, S Yan, SB Seidman, SD Reis, Sergey Brin, Sergey V. Buldyrev, T Martin, W Li, X Teng, X Teng, Y Hu, Y Liu, Y Liu   +74 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Alter ego, state of the art on user profiling: an overview of the most relevant organisational and behavioural aspects regarding User Profiling. [PDF]

, 2005
This report gives an overview of the most relevant organisational and\ud behavioural aspects regarding user profiling. It discusses not only the\ud most important aims of user profiling from both an organisation’s as\ud well as a user’s perspective, it ...
Dijk, J.A.G.M. van, Ebbers, W.E., Fennis, B.M., Geest, T.M. van der, Loorbach, N.R., Pieterson, W.J., Steehouder, M.F., Taal, E., Vries, P.W. de   +8 more
core   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Mathematical models of games of chance: Epistemological taxonomy and potential in problem-gambling research [PDF]

, 2015
Games of chance are developed in their physical consumer-ready form on the basis of mathematical models, which stand as the premises of their existence and represent their physical processes.
Barboianu, Catalin
core   +3 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source