Results 61 to 70 of about 5,406,248 (312)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Guidance on the self-assessment of a provider’s financial management and control arrangements using the financial management and control evaluation (FMCE) return: version 2, november 2010 [PDF]

, 2010
This guidance has been prepared for the providers that the Skills Funding Agency takes the “lead” for on assurance matters. However, it is also equally applicable to those providers that the YPLA directly funds and l takes the “lead” for on assurance ...

core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The Financial Crisis and Credit Unavailability: Cause or Effect? [PDF]

, 2017
Although the relationship between credit availability and financial decline leading to the global financial crisis was somewhat interactive, a loss of credit availability appears to have caused the financial crisis more than the reverse.
Schwarcz, Steven L.
core   +1 more source

Publicness, Organisational Characteristics and Performance [PDF]

, 2013
This paper reports an exploratory study utilising a publicness model in which the impact of ownership, funding and mode of control on performance is moderated by organisational characteristics such as goals, structure and management.
B.Bozeman, B.Bozeman, D. R.Dalton, G. A.Hodge, J. N.Baldwin, L.Donaldson, R. E.Ashworth, S.Kelman   +7 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Considerations regarding possible directions for improving the method of carrying out financial control in public institutions in Romania

Bulletin of "Carol I" National Defense University
This article aims to analyze the current state and the fundamental role of financial control within public entities in Romania. Through a methodology based on comparative analysis, the study focuses on financial control legislation and practices ...
Sebastian FLOȘTOIU
doaj   +1 more source

Parliamentary control over public finances as a type of financial control

Lex Portus, 2019
Financial control is a set of measures aimed at creating an effective system to counteract the misuse of state and municipal monetary resources. Ensuring the effectiveness of financial control is possible only when a qualitatively organized system of ...
Uliana Oleksii
doaj   +1 more source

FINANCIAL CONTROL EFFICIENCY IN ECONOMIC ENTITIES [PDF]

In this paper the author presents ways to address issues of financial control efficiency of economic entities through tax administration of budgetary revenues.financial control, fiscal control, economic ...
Pop Ioan
core  

Competitive Effects of Partial Ownership: Financial Interest and Corporate Control [PDF]

, 2000
In this article, we set up an economic framework for analyzing the competitive effects of partial ownership interests. We have three main goals. First, we conceptually derive and explain the competitive effects of partial ownership, explaining its key ...
O\u27Brien, Daniel P., Salop, Steven C.
core   +1 more source