Results 51 to 60 of about 532,340 (297)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Navigating Adoption of Financial Derivatives: Dynamics of Complexity and Regulatory System
Theory, Methodology, PracticeThis study examines the intention of financial institutions to adopt financial derivatives in less developed markets. Integrating key innovation attributes, complexity and regulatory system as a moderator.
Ruva Tunze +2 more
doaj +1 more source
A multi-dimensional FBSDE with quadratic generator and its applications
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015 We consider, in the Markovian framework, a multi-dimensional forward - back - ward stochastic differential equation with quadratic growth for the generator function of the backward system.
Rotenstein Eduard
doaj +1 more source
Faster Valuation of Financial Derivatives
The Journal of Portfolio Management, 1995 Monte Carlo simulation is widely used to value complex financial instruments. An alternative to Monte Carlo is to use "low discrepancy" methods. Theory suggests that low discrepancy methods might be superior to the Monte Carlo method. We compared the performance of low discrepancy methods with Monte Carlo on a Collateralized Mortgage Obligation (CMO ...
Paskov, Spassimir, Traub, Joseph F.
openaire +2 more sources
Temporal Aspects of Smart Contracts for Financial Derivatives
, 2018 Implementing smart contracts to automate the performance of high-value over-the-counter (OTC) financial derivatives is a formidable challenge. Due to the regulatory framework and the scale of financial risk if a contract were to go wrong, the performance
C Clack, D Magazzeni, N Rescher, RM Lee
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Model for Diversifying iGaming Through Financial Derivatives
InformationThe present study analyzes the possibilities for diversification in the iGaming sector through the integration of concepts derived from financial derivatives theory.
Petko Iliev, Daniela Orozova
doaj +1 more source
Hedge accounting under IFRS 9: an analysis of reforms
Audit Financiar, 2017 Pronouncements of regulatory bodies on ‘hedge accounting’ are aimed at ensuring that impact of price changes of hedging relationships are accounted for concurrently.
Jatinder Pal Singh
doaj +1 more source
Econometric analysis of financial derivatives: An overview [PDF]
Journal of Econometrics, 2015 One of the fastest growing areas in empirical finance, and also one of the least rigorously analyzed, especially from a financial econometrics perspective, is the econometric analysis of financial derivatives, which are typically complicated and difficult to analyze. The purpose of this special issue of the journal on “Econometric Analysis of Financial
Chia-Lin Chang, Michael McAleer
openaire +7 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source