Results 61 to 70 of about 2,003,580 (268)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Algorithmic overconfidence, financial literacy, and decision quality: comparative evidence from Morocco and France

Smart Cities and Regional Development Journal
The growing adoption of algorithmic financial technologies, including robo-advisors, automated trading platforms and artificial-intelligence-based decision tools, raises a fundamental question regarding their actual contribution to investor rationality ...
Chaimaa LAAMIME, Karima MIALE
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

NutBaaS: A Blockchain-as-a-Service Platform

IEEE Access, 2019
Blockchain, originated from Bitcoin system, has drawn intense attention from the academic community because of its decentralization, persistency, anonymity and auditability.
Weilin Zheng, Zibin Zheng, Xiangping Chen, Kemian Dai, Peishan Li, Renfei Chen   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

ANALYSIS OF RISK-BASED ASSET MANAGEMENT PLAN TO INCREASE PERFORMANCE OF WATER LOCAL COMPANY

Jurnal Bisnis dan Manajemen, 2019
This study aims to obtain the concept of risk-based asset management planning with consideration of government regulations and international standards of asset management that can improve the performance of Regional Water Company (PDAM) of Aceh Province.
Monita Mardika Fajar, Dian Masyita, Leni Susanti   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Analysis of Vulnerabilities That Can Occur When Generating One-Time Password

Applied Sciences, 2020
A one-time password (OTP) is a password that is valid for only one login session or transaction, in IT systems or digital devices. This is one of the human-centered security services and is commonly used for multi-factor authentication.
Hyunki Kim, Juhong Han, Chanil Park, Okyeon Yi   +3 more
doaj   +1 more source

Essays on Financial Development and Financial Inclusion [PDF]

, 2021
This PhD thesis contributes to our understanding about financial development, focusing on three main topics: (1) the link between financial deepening and financial stability; (2) the determinants of financial inclusion; and (3) the effect of financial inclusion on improving economic welfare, which have received less attention in the literature.
openaire   +2 more sources