Results 241 to 250 of about 448,706 (298)

Technological Innovation and Trade Orientation as Drivers of Renewable Energy Consumption: Panel Evidence from G7 Economies. [PDF]

Glob Chall
Yu M, Farooq U, Tabash MI, Aljughaiman AA, Almulhim AA.   +4 more
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Medicine for a Changing Planet: Online Clinical Cases in Planetary Health and Infectious Diseases. [PDF]

Open Forum Infect Dis
Judson SD, Ripp K, Benzekri NA, LaBeaud AD, Veidis E, Xie M, Tin A, Barry M, Rabinowitz P.   +8 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Climate variability, population growth, and globalization impacting food security in Pakistan. [PDF]

Sci Rep
Abbas S, Haider A, Kousar S, Lu H, Lu S, Liu F, Li H, Miao C, Feng W, Ahamad MI, Mehmood MS, Zulqarnain RM.   +11 more
europepmc   +1 more source

The impact of globalization, renewable energy, and labor on sustainable development: A cross-country analysis. [PDF]

PLoS One
Chuong HN, Uyen VTP, Ngan NDP, Tram NTB, Han NDM, Duyen PHK.   +5 more
europepmc   +1 more source

Leveraging disease outbreak news to strengthen the global response to antimicrobial resistance: a call for action. [PDF]

Front Public Health
Kiggundu R, Waswa JP, Mwanja H, Hope M, Kambugu A, Kakooza F, Byonanebye DM.   +6 more
europepmc   +1 more source

The Future of Enhanced Recovery After Surgery in General Surgery: Integrating Artificial Intelligence, Personalized Care, and Technological Advances. [PDF]

Cureus
Abosheisha M, Nasr E, Abdellatif M, Swealem A, Ammar A, Hasan MAS, Abdelglil M, Tamanna R, Ismaiel M.   +8 more
europepmc   +1 more source

China's global health diplomacy through the World Health Organization: a qualitative study. [PDF]

Global Health
Shang Z, Huang Y.
europepmc   +1 more source