Results 101 to 110 of about 3,263,562 (356)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Should we pay all smokers to quit smoking? A mixed methods survey exploring New Zealand smokers' perceptions of financial incentives

open access: yesTobacco Induced Diseases, 2018
Background Evidence suggests financial incentives can support smoking cessation among pregnant smokers and for employees in a workplace setting, yet low acceptability may limit the wider implementation of such schemes. The increasing adoption of endgame
Lindsay Robertson   +4 more
doaj   +1 more source

Financial incentives in disability insurance in the Netherlands [PDF]

open access: yes
In this paper, we assess the impact of financial incentives on the inflow in the public Disability Insurance (DI) scheme in the Netherlands. For this matter, the variation in replacement rates over different sectors is exploited to estimate the ...
Annemiek van Vuren, Daniel van Vuuren
core  

WHAT HAS HAPPENED TO REPLACEMENT RATES? ESRI Working Paper No. 76, May 1996 [PDF]

open access: yes, 1996
Financial incentives to take up and stay in work, and the impact of the tax and social welfare systems on these incentives, have become a major preoccupation of Irish policy-makers. Recent Budgets have highlighted measures to "reward work" through income
Callan, Tim   +2 more
core  

Quality of Care in the United Kingdom after Removal of Financial Incentives

open access: yesNew England Journal of Medicine, 2018
BACKGROUND The benefits of pay‐for‐performance schemes in improving the quality of care remain uncertain. There is little information on the effect of removing incentives from existing pay‐for‐performance schemes.
Mark Minchin   +4 more
semanticscholar   +1 more source

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

open access: yesFEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo   +4 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Parental Perspectives on Financial Incentives for Adolescents: Findings From Qualitative Interviews

open access: yesGlobal Pediatric Health, 2019
Background. Financial incentives are becoming more common to promote health behaviors; however, little is known about the acceptability of incentivizing adolescent health behaviors. Design.
Kera M. Beskin MPH, MBA   +1 more
doaj   +1 more source

Circuit theory of finance and the role of incentives in financial sector reform [PDF]

open access: yes
The author analyzes the financial system's role in economic growth and stability, addressing several core policy issues associated with financial sector reform in emerging economies.
Bossone, Biagio
core  

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

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