Results 71 to 80 of about 2,906,935 (302)

What can motivate Lady Health Workers in Pakistan to engage more actively in tuberculosis case-finding?

open access: yesBMC Public Health, 2019
Background Many interventions to motivate community health workers to perform better rely on financial incentives, even though it is not clear that monetary gain is the main motivational driver.
Mishal S. Khan   +6 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Incentivizing green building technology: A financial perspective on sustainable development in India [version 1; peer review: 2 approved, 1 approved with reservations]

open access: yesF1000Research
Future viability depends on ensuring a sustainable society because green energy methods may efficiently reduce greenhouse gas emissions. Nevertheless, stakeholders, consumers, and developers continue to be notably ignorant of the financial incentives ...
Tilottama Singh   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The Effect of Financial Incentives and Task-specific Cognitive Abilities on Task Performance [PDF]

open access: yes
We extend evidence on the interaction between financial incentives and cognitive abilities by focusing on the effect of task-specific abilities.
Ondrej Rydval
core  

Evaluating the impact of financial incentives on inequalities in smoking cessation in primary care [PDF]

open access: yes, 2013
Background: Smoking cessation interventions are underprovided in primary care. This thesis examines the impact of financial incentives on the provision of smoking cessation interventions, and inequalities in provision, in primary care.
Hamilton, Fiona Louise
core   +1 more source

Incentivizing green building technology: A financial perspective on sustainable development in India [version 2; peer review: 2 approved, 1 approved with reservations]

open access: yesF1000Research
Future viability depends on ensuring a sustainable society because green energy methods may efficiently reduce greenhouse gas emissions. Nevertheless, stakeholders, consumers, and developers continue to be notably ignorant of the financial incentives ...
Tilottama Singh   +5 more
doaj   +1 more source

The association of financial incentives for low density lipoprotein cholesterol reduction with patient activation and motivation

open access: yesPreventive Medicine Reports, 2019
There is growing interest in using financial incentives for patients to improve medication adherence, but few studies have evaluated whether financial incentives are associated with patients' activation and motivation.
Tianyu Liu   +9 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

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