Results 31 to 40 of about 3,184,143 (296)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Protection of the Rights of Individual Depositors in Ukrainian Banking Market

open access: yesFinanse i Prawo Finansowe, 2016
The complex analysis of deposit operations of individuals in Ukraine was realized. The national legal norms of protection the rights of investors – individuals were investigated.
Sophia Lobozynska
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

THE THEORY OF FINANCIAL INNOVATIONS. A CRITICAL REVIEW OF PRINCIPAL APPROACHES

open access: yesФинансы: теория и практика, 2017
In times of crises, attempts are often made to blame all the troubles on financial innovations and reconsider their role in the progress. At the same time scientific publications also discuss positive aspects of financial innovations.
M. V. Sigova, I. K. Klyuchnikov
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Fraud Disclosure Tendency in Banking System: Impact of Psychological Contract Breach and Organizational Factors [PDF]

open access: yesIranian Journal of Accounting, Auditing & Finance
This study addresses the impact of psychological contract breaches and organizational factors on fraud disclosure in the banking system. The statistical population includes all the employees and internal auditors in the banks listed on the stock exchange
Ali Sheikhi, Amin Nazemi
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Banking concentration and financial reorganization: Greece, Portugal, and Spain in the post-crisis period

open access: yesPSL Quarterly Review, 2020
This article aims to analyze how banking concentration and financial reorganization have occurred during the post-crisis period in Greece, Portugal and Spain, highlighting the continuity of three worrisome trends related to financial stability: an ...
Alicia Girón   +2 more
doaj  

BRAZILIAN FINANCIAL CRISIS IN THE 1980S: HISTORICAL PRECEDENT OF AN ECONOMY GOVERNED BY FINANCIAL INTERESTS

open access: yesRevista de Economia Contemporânea, 2019
Beyond representing coordination or government failures, the Brazilian financial crisis in the 1980s characterized the dominance of financial interests on public policies.
Fabiano Abranches Silva Dalto
doaj   +1 more source

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