Results 61 to 70 of about 4,650,691 (252)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Structural modification of supply chains in the imperatives of circular economy
Journal of Innovation and EntrepreneurshipGlobal economic and environmental challenges in the development of contemporary society underscore the importance of addressing issues related to the structural modification of supply chains within the context of a circular economy. The goal of the study
Ivan Kudrenko +2 more
doaj +1 more source
Strategic planning in financial institutions
South African Journal of Business Management, 1982 The article outlines an approach to strategic planning for financial institutions in which functional strategic plans are first developed for each business unit or unique area of service in the organization.
Kenneth C. Krogh
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Unexpected Outcomes of the Financial Institutions Act [PDF]
The Financial Institutions Act of 1992 provided a new legislative and regulatory framework for non-bank deposit-taking financial institutions (NBFIs), Building Societies and Credit Unions.
Dr Jon D. Stanford
core
Verimlilik DergisiPurpose: Non-bank financial institutions can contribute to the deepening and diversification of financial markets by providing broader access to credit, insurance, and investment services.
Bertaç Şakir Şahin
doaj +1 more source
EL PAPEL DE LA INFORMACIÓN FINANCIERA EN LA EVOLUCIÓN RECIENTE DEL SECTOR BANCARIO ESPAÑOL
Revista de Estudios Empresariales. Segunda Época, 2016 This paper is dedicated to analyze the large number of measures taken on the Spanish financial system before the economic crisis of recent years and to study their impact on financial strategies of financial institutions, in an attempt to adapt to such
Mª del Consuelo Ruiz Rodríguez +1 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Games, 2017 This paper experimentally investigates how monetary incentives and emotions influence behavior in a two-player power-to-take game (PTTG). In this game, one player can claim any part of the other's endowment (take rate), and the second player can respond ...
Ronald Bosman +2 more
doaj +1 more source