Results 41 to 50 of about 1,535,447 (303)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Financial Instruments: the Essence, Diversity and Role in the Process of Modernization of the Electric Power Sector [PDF]
The aim of the article is to clarify the methodological basis for further research concerning analysis of the existing practices and development of proposals on using financial instruments for the modernization of the Ukrainian electric power sector, in ...
Abakumenko Olha V., Lukiashko Pavlo O.
doaj
Current Issues Regarding the Recording in Accounting of the Financial Instruments for Financing the Activity of the Entities [PDF]
The use of financial instruments is a relatively small phenomenon in the context of the current Romanian economy. However, we can see an increase in the use of financial instruments to finance the current and future activities of entities in the national
Traian Cristin Nicolae
doaj
Financial instability from local market measures
We study the emergence of instabilities in a stylized model of a financial market, when different market actors calculate prices according to different (local) market measures.
Albanese C +12 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Conceptual Approaches in Financial Instruments Sphere [PDF]
The article examines the conceptual approaches in the sphere of financial instrumentsaccording to international regulations. The article analyzes the conceptual boundaries of financialinstruments, their classification into financial asset, financial ...
Georgeta Covaliov-Rusu
doaj
Financial literacy : an essential tool for informed consumer choice? [PDF]
Increasingly, individuals are in charge of their own financial security and are confronted with ever more complex financial instruments. However, there is evidence that many individuals are not well-equipped to make sound saving decisions.
Lusardi, Annamaria
core +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Monetary Instruments and the Control of Liquidity in the Philippines: Focus on Open Market Operations [PDF]
Monetary policies refer to the actions of central banks aimed to achieve macroeconomic stability and to influence financial factors such as money and interest rate. This paper discusses the framework for analyzing how monetary instruments affect monetary
San Jose, Armida S.
core +2 more sources
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

