Results 41 to 50 of about 1,535,447 (303)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Financial Instruments: the Essence, Diversity and Role in the Process of Modernization of the Electric Power Sector [PDF]

open access: yesProblemi Ekonomiki, 2017
The aim of the article is to clarify the methodological basis for further research concerning analysis of the existing practices and development of proposals on using financial instruments for the modernization of the Ukrainian electric power sector, in ...
Abakumenko Olha V., Lukiashko Pavlo O.
doaj  

Current Issues Regarding the Recording in Accounting of the Financial Instruments for Financing the Activity of the Entities [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2021
The use of financial instruments is a relatively small phenomenon in the context of the current Romanian economy. However, we can see an increase in the use of financial instruments to finance the current and future activities of entities in the national
Traian Cristin Nicolae
doaj  

Financial instability from local market measures

open access: yes, 2012
We study the emergence of instabilities in a stylized model of a financial market, when different market actors calculate prices according to different (local) market measures.
Albanese C   +12 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Conceptual Approaches in Financial Instruments Sphere [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2016
The article examines the conceptual approaches in the sphere of financial instrumentsaccording to international regulations. The article analyzes the conceptual boundaries of financialinstruments, their classification into financial asset, financial ...
Georgeta Covaliov-Rusu
doaj  

Financial literacy : an essential tool for informed consumer choice? [PDF]

open access: yes, 2008
Increasingly, individuals are in charge of their own financial security and are confronted with ever more complex financial instruments. However, there is evidence that many individuals are not well-equipped to make sound saving decisions.
Lusardi, Annamaria
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Monetary Instruments and the Control of Liquidity in the Philippines: Focus on Open Market Operations [PDF]

open access: yes
Monetary policies refer to the actions of central banks aimed to achieve macroeconomic stability and to influence financial factors such as money and interest rate. This paper discusses the framework for analyzing how monetary instruments affect monetary
San Jose, Armida S.
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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