Results 71 to 80 of about 461,293 (266)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Investigating the critical role of Hormuud’s EVC-Plus mobile money in augmenting the delivery of lifesaving humanitarian aid in Somalia

open access: yesFrontiers in Human Dynamics
This study investigates the pivotal role of Hormuud Telecom’s EVC-Plus mobile money platform in enhancing the delivery of lifesaving humanitarian aid in Somalia, one of the world’s most fragile states. It examines how operational accessibility, financial
Mohamed Ibrahim Nor
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Stock market interrelationships in the Latin American Integrated Market (MILA): a VAR approach to short-term dynamics (2015–2022)

open access: yesTendencias
Introduction: This study is part of the analysis of the Latin American Integrated Market (MILA) made up of the Peruvian, Chilean and Colombian stock exchanges since 2011, and expanded in 2014 with the incorporation of Mexico.
Luis Enrique Cayatopa-Rivera   +1 more
doaj   +1 more source

Financial Integration and Consumption Smoothing in Nigeria and Egypt: Do Global Uncertainties Matter? [PDF]

open access: yesMeđunarodna politika
In this study, we adopt the structural vector auto-regressive (SVAR) model to assess the degree to which global uncertainties affect the relationship between financial integration and consumption smoothing in Egypt and Nigeria using quarterly data ...
Emeka Okoro Akpa   +1 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Interest Rate Pass‑through and Monetary Policy Transmission in SADC and EAC Countries: Implications for Monetary Union

open access: yesComparative Economic Research
Southern African Development Community (SADC) and East African Community (EAC) countries are exploring the feasibility of establishing a monetary union.
Damilola Oyetade   +2 more
doaj   +1 more source

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