Results 41 to 50 of about 102,530 (287)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

International financial intermediation: implications for bankers and regulators

open access: yesPSL Quarterly Review, 2013
The growth of international financial intermediation through the Euromarket and other regional financial centres is one of the most remarkable phenomena of the last 15 years.
C. DEMATTÈ
doaj   +1 more source

Can Financial Development Cause Financial Instability?

open access: yesRevue des Etudes Multidisciplinaires en Sciences Economiques et Sociales, 2020
The objective of this article consists to identify which determinants of financial development can cause financial instability and if these determinants depend on the economic development degree of the country.
Feryel OUERGHI, Tayssir OUESLETI
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Impact of Financial Intermediation and Financial Sector Efficiency on Economic Growth in Pakistan

open access: yesJISR Management and Social Sciences & Economics, 2019
The financial sector plays a significant role in the economic development of a country. The aim of the study is to investigate the impact of financial intermediation and financial sector efficiency on economic growth in Pakistan. The study examines time
Adiqa Kiani, Muhammad Ali
doaj   +1 more source

Influence of financial intermediation institutes on the welfare of the population in the post-Soviet countries: A comparative analysis

open access: yesCogent Social Sciences, 2023
Throughout the history of the development of the economy, financial intermediation has performed the functions of reducing transaction costs, having a stimulating effect on the economic system.
Karen Vladimirovich Turyan
doaj   +1 more source

Essays on financial intermediation [PDF]

open access: yes, 2019
This thesis is structured around two main chapters that study how financial intermediaries affect asset prices and real economic activity of firms. In the first chapter, I study how mutual fund managers affect asset prices due to two types of risk they have to face: fund flow risk and liquidity risk. Uncertain fund flows affect managers' income and may
openaire   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

FINANCIAL INTERMEDIATION AFTER THE FINANCIAL CRISIS [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2017
The purpose of this paper is to provide a perspective on financial intermediation in the Romanian banking system and bank profitability during and after the financial crisis.
IMOLA DRIGĂ
doaj  

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