Results 51 to 60 of about 102,530 (287)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

FINANCIAL INTERMEDIATION SECTOR IN INDONESIA’S PRODUCTION PYRAMID

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2017
This paper investigates the importance of financial intermediation sector in the inter-industry context, using input-output tables from 1995, 2000, 2005, and 2010.
Martin Panggabean
doaj   +1 more source

Endogenous Growth Model With Financial Intermediation

open access: yesStudia Humana, 2021
In this paper, we analyse the simplest possible three-dimensional model of endogenous growth to account for the relationship between financial intermediation and economic growth.
Byrska Dominika
doaj   +1 more source

Testing the finance-growth link: is there a difference between developed and developing countries? [PDF]

open access: yes
We revisit the evidence of the existence of a long -run link between financial intermediation and economic growth, by testing of cointegration between the growth rate of real GDP, control variables and three series reflecting financial intermediation. We
Anne Peguin-Feissolle   +2 more
core   +3 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Debt covenant and financial intermediation: how debt characteristics shape earnings management in Vietnam [PDF]

open access: yesJournal of Economics and Development
PurposeThis study refines debt covenant, financial intermediation and information economics theories by examining how debt maturity and sources shape earnings management (EM) in emerging markets.Design/methodology/approachUsing Vietnam’s bank-dominated ...
Cong Phuong Nguyen   +1 more
doaj   +1 more source

The Role of Barriers to the Activity of Industrial Enterprises in the Evaluation of the Business Tendency in Poland

open access: yesFolia Oeconomica Stetinensia, 2020
Research background: Surveys of entrepreneurs regarding the assessment of conditions for conducting business activity are carried out by several institutions.
Kaźmierska-Zatoń Maria   +1 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Intermediation Cost and Non-Performing Financing: A Case Study of Pakistan

open access: yesJISR Management and Social Sciences & Economics, 2010
The instinct of bankers is to keep the borrowers alive through recycling and renewals of bad loans into loans, a window dressing exercise; or worse yet, advancing additional fresh loans to effectively insolvent borrowers to tide over what is  perceived ...
Azam Ali
doaj   +1 more source

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