Results 141 to 150 of about 2,193,222 (326)

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

Re-thinking commercial real estate market segmentation [PDF]

, 2010
Investments in direct real estate are inherently difficult to segment compared to other asset classes due to the complex and heterogeneous nature of the asset.
Fuerst, Franz, Marcato, Gianluca
core  

Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries

Advanced Science, EarlyView.
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang, Wenkai Wang, Zhenling Peng, Jianyi Yang   +3 more
wiley   +1 more source

Pre-letting of office developments : a guide for occupiers [PDF]

, 2007
‘Pre-letting’ is an agreement between a potential tenant and a developer to lease a building whose construction has not yet started. Benefits typically flow to both parties from a pre-letting, however, opportunities to pre-let are limited by place, time,
Cooke, Howard, Fisher, Peter, Morley, S.
core  

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Advantages and disadvantages of leasing

Contemporary Economy, 2012
The article is systematization of knowledge on leasing as a source of financing for enterprises. This paper defines the leasing and presented its nature according to the norms of civil, tax and accounting law.
Katarzyna Wiśniewska
doaj  

A Decision-Support Framework For Using Value Capture to Fund Public Transit: Lessons From Project-Specific Analyses, Research Report 11-14 [PDF]

, 2012
Local and state governments provide 75 percent of transit funds in the United States. With all levels of governments under significant fiscal stress, any new transit funding mechanism is welcome. Value capture (VC) is one such mechanism.
Mathur, Shishir, Smith, Adam
core   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source

Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro

Advanced Science, EarlyView.
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner, Petra B. Welzel, Maximilian Fusenig, Linda Sturm, Dagmar Pette, Wolfgang Wagermaier, Claudia Fischbach, Peter Fratzl, Carsten Werner   +8 more
wiley   +1 more source

El Tratamiento Contable y los Efectos Financieros y Fiscales de los Arrendamientos

Tec Empresarial, 2013
En Costa Rica el mercado de los arrendamientos esuno de los sectores que durante los últimos años hamostrado mayor consolidación y crecimiento y cuyoimpacto ha sido sumamente significativo tanto sobrela posición financiera, resultado de operación y ...
Vernor Mesén Figueroa
doaj