Results 81 to 90 of about 1,352,480 (299)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Fractal-Based Robotic Trading Strategies Using Detrended Fluctuation Analysis and Fractional Derivatives: A Case Study in the Energy Market

Fractal and Fractional
This paper presents an integrated robotic trading strategy developed for the day-ahead energy market that includes different methods for time series analysis and forecasting, such as Detrended Fluctuation Analysis (DFA), Rescaled Range Analysis (R/S ...
Ekaterina Popovska, Galya Georgieva-Tsaneva   +1 more
doaj   +1 more source

Does financial activity cause economic growth? [PDF]

To clarify the causal links between financial activity and economic growth, three theoretical models are analyzed and a structural equation path models is estimated. In the modeling part, poverty traps result from large fixed costs or high proportions of
Graff, Michael, Karmann, Alexander
core  

Point Processes Modeling of Time Series Exhibiting Power-Law Statistics

, 2007
We consider stochastic point processes generating time series exhibiting power laws of spectrum and distribution density (Phys. Rev. E 71, 051105 (2005)) and apply them for modeling the trading activity in the financial markets and for the frequencies of
Alaburda, M., Gontis, V., Kaulakys, B.
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Anchor-Based Explainable and Causal Artificial Intelligence for Enhancing Financial Predictions of Future Earnings

IEEE Access
Accurate prediction of future earnings is crucial for stakeholders. However, existing machine learning models often operate as “black boxes,” offering high accuracy but minimal interpretability.
Siriporn Sawangarreerak, Putthiporn Thanathamathee, Pankaewta Lakkanawanit, Nor Shaipah Abdul Wahab   +3 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Forecasting IHSG Stock Prices Using an Attention-Based CNN-BiGRU Hybrid Deep Learning

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi)
This study develops an IHSG stock price forecasting model using a hybrid CNN–BiGRU architecture enhanced by an attention mechanism. The key novelty lies in combining CNN-based local pattern extraction with BiGRU-based bidirectional temporal modeling ...
Ibnu Rasyid Munthe, Bhakti Helvi Rambe, Shabrina Rasyid Munthe   +2 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

BANKS FINANCIAL SECURITY MANAGEMENT: MODELING TOOLS

Фінансово-кредитна діяльність: проблеми теорії та практики, 2017
The article is devoted to the development of the complex of economic and mathematical models to support decision–making on managing commercial banks financial security.
О. А. Sergienko, M. S. Tatar, N. L. Morozova, R. V. Galych   +3 more
doaj   +1 more source