Results 61 to 70 of about 2,699,166 (256)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Endogenous Financial and Trade Openness [PDF]

open access: yes
This paper studies the endogenous determination of financial and trade openness. First, we outline a theoretical framework leading to two-way feedbacks between the different modes of openness; next, we identify these feedbacks empirically.
Ilan Noy, Joshua Aizenman
core  

Financial openness and energy structure transformation

open access: yesFrontiers in Environmental Science
Energy structure transformation is the only way for China to achieve the “dual carbon” goal, and one of the difficulties faced by energy transformation is financing.
Xianjun Jia, Wenjing Xu, Kaiyue Wang
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Openness and Growth Volatility [PDF]

open access: yes
Macroeconomic volatility is the outcome of countries’ exposure to shocks (the magnitude and frequency of shocks that hit their economies) and their vulnerability (the ability to respond to these shocks).
Klaus Schmidt-Hebbel, César Calderón
core  

Financial Development, Openness and Institutions: Evidence from Panel Data [PDF]

open access: yes
Utilising four annual panel datasets and dynamic panel data estimation procedures we find that trade and financial openness, as well as economic institutions are statistically important determinants of the variation in financial development across ...
Badi H. Baltagi   +2 more
core   +2 more sources

Facilitator or inhibitor?

open access: yesInternational Review of Economics & Finance
The relationship between financial openness and economic growth has long been debated, with empirical evidence remaining mixed. Much of the existing literature focuses on the late 20th century, leaving the effects of financial openness in the 21st ...
Dominik Ulke
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Financial Openness and Remittances: Evidence from Sub-Saharan Africa

open access: yes, 2022
Does financial openness matter for remittances? Are the effects of financial openness on remittance dependent on the levels of financial and institutional development?
Effiong, Ekpeno L., Asuquo, Emmanuel E.
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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