Results 41 to 50 of about 2,284,054 (293)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Benchmarking Health Systems in Middle Eastern and North African Countries

open access: yesHealth Systems & Reform, 2017
—Health systems are not easy to benchmark, in part because the health sector produces more than one outcome. This article offers two ways of benchmarking the health systems of countries in the Middle East and North Africa (MENA) focusing on two different
Huihui Wang, Abdo S. Yazbeck
doaj   +1 more source

Comparing the Paulson Blueprint With the Geithner White Paper [PDF]

open access: yes, 2009
Compares the financial reform recommendations and discussions of structural financial models from Treasury Department officials of the Bush and Obama administrations.
Gordon McDonald
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

The Campus Debit Card Trap: Are Bank Partnerships Fair to Students? [PDF]

open access: yes, 2012
Examines partnerships between colleges and financial firms on campus ID, prepaid, debit, and financial aid disbursement cards and questions about fees, aggressive marketing strategies, and consumer protection.
Donna Cooper, Kristina Costa
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

A Review of the Health Financing Policies Towards Universal Health Coverage in Iran

open access: yesمجله اپیدمیولوژی ایران, 2017
Background and Objectives: Timely access to required health services without any financial hardship is necessary to achieve public health. Therefore, the aim of present study was to review the policies and plans adopted in the health financing system ...
MH Mehrolhassani   +6 more
doaj  

UNEMPLOYMENT IN HUNEDOARA COUNTY [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2015
Unemployment highlights a state of imbalance on the labour market which is characterized by a surplus of workforce in relation to job vacancies. This imbalance has been more apparent in Hunedoara County than in other counties, due to the fact that there ...
CLAUDIA ISAC, ALINA NIȚESCU
doaj  

Health Financing Reforms for Moving towards Universal Health Coverage in the Western Pacific Region

open access: yesHealth Systems & Reform, 2019
This article provides an overview of health financing reforms across countries in the Western Pacific Region as progress is made toward universal health coverage (UHC).
Annie Chu, Soonman Kwon, Peter Cowley
doaj   +1 more source

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