Results 61 to 70 of about 251,825 (264)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

FINANCIAL PROVISION OF RUSSIAN ECONOMY MODERNIZATION

Вестник Донского государственного технического университета, 2018
The use of budget funds, direct investment funds, and venture capital funds as the major sources of the modernization financial assets is analyzed. General financial instruments for stimulating the Russian economy modernization are specified.
Igor A. Yeremenko, Elena N. Rudskaya
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

ON THE PROBLEMS OF FINANCIAL PROVISION OF FREE PROVISION OF MEDICAL CARE IN RUSSIA

AZIMUTH OF SCIENTIFIC RESEARCH: ECONOMICS AND ADMINISTRATION, 2021
Domestic health care, which is currently at the next stage of modernization, has a number of problems caused by insufficient financial support and inadequacy of the medical care provided to the criteria of quality and availability. The current situation, with the greatest degree of probability, is associated with the imperfection of the model of ...
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

FINANCIAL PROVISION OF EDUCATIONAL SYSTEMS OF HIGHER PROFESSIONAL EDUCATION

Russian Journal of Economics and Law, 2012
The article views the organization-economic features of financial provision of the modern economic systems on the example of higher professional educational establishments.
G. I. Magomedov, D. Y. Mamyrkin, G. G. Karasyov   +2 more
doaj  

Financial Centrality and Liquidity Provision

, 2018
We study an endowment economy in which agents face income risk, as if uncertain returns on a portfolio, and agents can only make transfers in states when they are actively participating in the market. Besides income risk, agents also have limited and stochastic market access, with a probability distribution governed by an underlying social network ...
Arun Chandrasekhar, Robert Townsend, Juan Pablo Xandri   +2 more
openaire   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

TAX OPTIMIZATION AS A DECISIVE FACTOR OF ECONOMIC DEVELOPMENT (THE CASE OF POLAND)

Baltic Journal of Economic Studies, 2016
The main purpose of the paper is to compare the system of taxation and tax optimization in Poland with solutions in the selected EU Member States and its influence on economic development. The paper presents the system of taxation in Poland compared with
Mykola Andriyash
doaj