Results 81 to 90 of about 4,899,973 (339)
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó +17 more
wiley +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source
The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh +22 more
wiley +1 more source
Paid in Full: A Critical Look at the Law and Economics of the Football Creditors Rule
Entertainment and Sports Law Journal, 2016 The Football League has recently modified its Football Creditors Rule. Once the sport’s financial regulatory bête noire, the changes met with little fanfare.
Christopher Flanagan
doaj +2 more sources
Inclusive banking, financial regulation and bank performance: Cross-country evidence
Journal of Banking & Finance, 2021 M. Ahamed +3 more
semanticscholar +1 more source
Practice Recommendations for Genetic Testing of Ataxias
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan +7 more
wiley +1 more source
REGULATING FINTECH IN CANADA AND THE UNITED STATES: COMPARISON, CHALLENGES AND OPPORTUNITIES
The School of Public Policy Publications, 2019 The rise of fintech has attracted increased attention from investors, entrepreneurs, existing financial-sector participants and regulators. Fintech has many potential benefits and it could transform banking, lending, payments, investing and other ...
Ryan Clements
doaj +1 more source
Economic Sanctions and Russia’s Financial System
Финансы: теория и практика, 2017 Topic. The problem of functioning of the financial system in the face of uncertainty is complicated by the entered by Western countries anti-Russian economic sanctions.
Igor N. Molchanov
doaj +1 more source
Metarules, Judgment and the Algorithmic Future of Financial Regulation in the UK. [PDF]
Oxf J Leg Stud, 2023 Georgosouli A.
europepmc +1 more source
Regulating Financial Market Infrastructures [PDF]
, 2015 This paper focuses on the impact of financial market infrastructures (FMIs) and of their regulation on the post-crisis transformation of securities and derivatives markets. It examines, in particular, the role that trading and post-trading FMIs, and their new regulatory regime, are playing in the expansion of ‘public’ securities and derivatives markets,
Niamh Moloney +4 more
openaire +3 more sources