Results 51 to 60 of about 16,939,992 (374)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Industry 4.0 in Finance: The Impact of Artificial Intelligence (AI) on Digital Financial Inclusion

open access: yesInternational Journal of Financial Studies, 2020
This study sought to investigate the impact of AI on digital financial inclusion. Digital financial inclusion is becoming central in the debate on how to ensure that people who are at the lower levels of the pyramid become financially active.
David Mhlanga
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

QUALITATIVE CHARACTERISTICS AND PRINCIPLESOF FINANCIAL REPORTS IN THE CONTEXT OF DISCLOSUREOF INFORMATION ABOUT THE ENTERPRISE AS A SUBJECTOF TAX RELATIONS

open access: yesEconomics & Education, 2016
In the article ways of information visibility provision concerning tax relations of the enterprise in the system of accounting and financial report are investigated. It is substantiated that necessity of information disclosure about tax relations of the
Nataliia Shalimova, Halyna Kuzmenko
doaj  

Thriving amidst uncertainty: a financial blueprint for the public budget

open access: yesPublic Sector Economics
This research explores strategies for thriving amidst uncertainty through a financial blueprint for public budgets, focusing on key factors like budgetary resilience (BR), stability (BS), sustainability (BSu), empowerment (BE), preparedness (BP ...
Enkeleda Lulaj
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Usability criteria for Business Intelligence Reports in the South African banking industry

open access: yesSouth African Journal of Information Management
Background: The South African banking sector is renowned as world-class, exhibiting ample capital, cutting-edge technology, robust infrastructure, and a rigorous regulatory and supervisory framework.
Pheladi A. Lebotsa   +2 more
doaj   +1 more source

Homer Foundation - 2007 Annual Report [PDF]

open access: yes, 2007
Contains mission statement, director's message, program information, financial statements, reports from the distributions and investment committees, grants list, donor information, and list of board ...

core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Factors Affecting Unqualified Financial Reports [PDF]

open access: yesمطالعات تجربی حسابداری مالی, 2006
The financial statements accompanied by independent auditors’ unqualified report which presents to capital market are used by interested beneficiary users. According to rules and regulations of the capital market, acceptance of the companies in the stock
Abbas Hoshi
doaj  

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